C1Q, HUMAN
- CAS No.
- 80295-33-6
- Chemical Name:
- C1Q, HUMAN
- Synonyms
- C1Q, HUMAN;COMPLEMENT 1Q;COMPLEMENT 1Q, HUMAN;COMPLEMENT C1Q, HUMAN;COMPLEMENT C1Q PROTEIN;COMPLEMENT COMPONENT C1Q;COMPLEMENT C1Q PROTEIN HUMAN;COMPLEMENT COMPONENT C1Q FROM HUMAN*SERUM;activity:18-30units/mgproteinsalt-free,lyophilizedsolidbysds
- CBNumber:
- CB2270821
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00130851
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Hazard Codes | B |
|---|---|
| WGK Germany | 3 |
C1Q, HUMAN price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C1740 | Complement component C1q from human serum ≥95% (SDS-PAGE) | 80295-33-6 | 0.5mg | $442 | 2024-03-01 | Buy |
| Sigma-Aldrich | 204876 | Complement C1q, Human | 80295-33-6 | 1mg | $489 | 2024-03-01 | Buy |
| Sigma-Aldrich | C1740 | Complement component C1q from human serum ≥95% (SDS-PAGE) | 80295-33-6 | 1mg | $764 | 2024-03-01 | Buy |
| Usbiological | 365874 | Complement 1q | 80295-33-6 | 96Tests | $824 | 2021-12-16 | Buy |
| Usbiological | C0010-02H | Complement C1q, Human | 80295-33-6 | 1mg | $874 | 2021-12-16 | Buy |
C1Q, HUMAN Chemical Properties,Uses,Production
Uses
Complement component C1q is an important regulator factor for platelet activation. This has been a topic for research, as platelet-leukocyte aggregates play an important role in inflammatory conditions such as coronary heart disease. In particular, C1q has been shown to inhibit collagen induced aggregation and enhance production of reactive oxygen species (ROS).
General Description
C1q, together with C1r and C1s, in the ratio of 1:2:2, form the C1 complex which is the first component of the classical complement pathway. C1q is composed of 18 polypeptide chains (six A, six B, six C) (MW 460 kDa). All contain an 81-aa collagen-like region composed of (Gly-Xaa-Yaa) repeating sequences close to the N-terminus. Three chains (A1B1C1) form a triple helix with the C-terminus forming the globular heads which may be structurally and functionally distinct domains.
Biochem/physiol Actions
≥150,000 C1qH50 units/mg and ≥70% C1q activity in normal human serum on a mg/mg basis
C1Q, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
C1Q, HUMAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai Yingxin laboratory equipment Co., Ltd | 021-021-59178156 15300768757 | 359382369@qq.com | China | 10367 | 58 |
| Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9849 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
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