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JNJ5207787

JNJ5207787 化学構造式
683746-68-1
CAS番号.
683746-68-1
化学名:
JNJ5207787
别名:
JNJ5207787
英語名:
(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide
英語别名:
JNJ 5207787;(E)-N-(1-acetyl-2,3-dihydroindol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]prop-2-enamide;trans-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]acrylamide;(2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide;2-Propenamide, N-(1-acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-, (2E)-
CBNumber:
CB32518575
化学式:
C32H38N4O2
分子量:
511
MOL File:
683746-68-1.mol

JNJ5207787 物理性質

比重(密度) :
1.22
貯蔵温度 :
Store at RT
溶解性:
Soluble to 10 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming
外見 :
Powder

安全性情報

JNJ5207787 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC4018 JNJ5207787
JNJ 5207787 		683746-68-1 10mg ￥99000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC4018 JNJ5207787
JNJ 5207787 		683746-68-1 50mg ￥389000 2024-03-01 購入

JNJ5207787 化学特性,用途語,生産方法

説明

JNJ-5207787 is an antagonist of the neuropeptide Y (NPY) receptor Y2 that blocks peptide YY binding (IC50 = 100 nM). It displays 100-fold selectivity for Y2 over other NPY receptors and has minimal effect on a panel of 50 receptors, ion channels, and transporters, except for sodium channel 2. JNJ-5207787 is intraperitoneally bioavailable and brain penetrant in rats, occupying maximally 50% of Y2 receptor binding sites in the hypothalamic area.

使用

JNJ 5207787 is a small molecule antagonist of the neuropeptide Y Y2 receptor.

JNJ5207787 上流と下流の製品情報

原材料

準備製品

JNJ5207787 生産企業

Global( 21)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Aladdin Scientific 		+1-833-552-7181
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15848 69
Amatek Scientific Co. Ltd. 0512-56316828
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BOC Sciences --
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11289 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
 sales@chemhifuture.com China 4030 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 8740 58
ApexBio Technology --
 sales@apexbt.com United States 6254 58
  • 683746-68-1
  • (2E)-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-2-propenamide
  • JNJ 5207787
  • trans-N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]acrylamide
  • (E)-N-(1-acetyl-2,3-dihydroindol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)piperidin-4-yl]prop-2-enamide
  • 2-Propenamide, N-(1-acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyanophenyl)-N-[1-(2-cyclopentylethyl)-4-piperidinyl]-, (2E)-
  • JNJ5207787
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