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1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-

化学構造式
509102-00-5
CAS番号.
509102-00-5
化学名:
别名:
英語名:
1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-
英語别名:
MIM1;CS-1192;MIM 1;MIM-1;Inhibitor of Mcl-1;1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-;4-[[[2-(Cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-1,2,3-benzenetriol;inhibit,Bcl-2 Family,Inhibitor of Mcl1,Inhibitor,MIM-1,MIM1,MIM 1,Inhibitor of Mcl 1;1,2,3-Benzenetriol, 4-[[[2-(cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-
CBNumber:
CB32652150
化学式:
C17H21N3O3S
分子量:
347.43
MOL File:
509102-00-5.mol

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- 物理性質

沸点 :
559.6±60.0 °C(Predicted)
比重(密度) :
1.40±0.1 g/cm3(Predicted)
溶解性:
insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL in DMSO
外見 :
A crystalline solid
酸解離定数(Pka):
7.73±0.45(Predicted)

安全性情報

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- 化学特性,用途語,生産方法

説明

MIM1 is an inhibitor of Mcl-1, an antiapoptotic Bcl-2 family protein with a role in cancer. It selectively engages the canonical groove of Mcl-1, inhibiting its ability to bind BH3 domains (IC50 = 4.7 μM). MIM1 induces caspase-3/7 activation and cell death in Mcl-1-dependent leukemia cells.

使用

MIM1 binds to MCL-1 and aids in the modulation of cell death, division and differentiation. MIM1 may be used for treating hyperproliferative disorders, angiogenesis disorders, cell cycle regulation disorders, autophagy regulation disorders, inflammatory disorders, and/or infectious disorders.

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- 上流と下流の製品情報

原材料

準備製品

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4- 生産企業

Global( 53)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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Career Henan Chemica Co 		+86-0371-86658258 15093356674;
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Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
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Aladdin Scientific 		+1-833-552-7181
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Amadis Chemical Company Limited 		571-89925085
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MedChemexpress LLC 021-58955995
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EMMX Biotechnology LLC 888-539-0666
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Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921
sales@pharmacodia.com China 2317 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9709 58

  スペクトルデータ(MS)

1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-(509102-00-5)MS

509102-00-5()キーワード:

メチルシクロヘキサン
  • 509102-00-5
  • MIM1
  • 4-[[[2-(Cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-1,2,3-benzenetriol
  • 1,2,3-Benzenetriol, 4-[[[2-(cyclohexyliMino)-4-
  • MIM 1;MIM-1
  • CS-1192
  • Inhibitor of Mcl-1
  • 1,2,3-Benzenetriol, 4-[[[2-(cyclohexylimino)-4-methyl-3(2H)-thiazolyl]imino]methyl]-
  • inhibit,Bcl-2 Family,Inhibitor of Mcl1,Inhibitor,MIM-1,MIM1,MIM 1,Inhibitor of Mcl 1
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