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副腎皮質刺激ホルモン FROM PORCINE PITUITARY

副腎皮質刺激ホルモン FROM PORCINE PITUITARY 化学構造式
9061-27-2
CAS番号.
9061-27-2
化学名:
副腎皮質刺激ホルモン FROM PORCINE PITUITARY
别名:
副腎皮質刺激ホルモン FROM PORCINE PITUITARY
英語名:
Adrenocorticotropic hormone
英語别名:
ACTH 1-39;CORTICOTROPIN A;ACTH (1-39), PORCINE;ADRENOCORTICOTROPIC HORMONE;ADRENOCORTICOTROPIC HORMONE;alpha1-39-Corticotropin (pig);PORCINE ADRENOCORTICOTROPIC HORMONE;AdrenocorticotrophicHormone,Porcine;ADRENOCORTICOTROPIC HORMONE, PORCINE;ADRENOCORTICOTROPIC HORMONE PORCINE PITUITARY
CBNumber:
CB3452071
化学式:
C210H314N56O57S
分子量:
4567.14616
MOL File:
9061-27-2.mol

副腎皮質刺激ホルモン FROM PORCINE PITUITARY 物理性質

貯蔵温度 :
−20°C
外見 :
粉
InChIKey:
XFBDTKGDXZDJAN-WODOTNDISA-N
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
主な危険性  Xn
Rフレーズ  20/21/22-40
Sフレーズ  22-36
WGK Germany  3
絵表示（GHS） GHS hazard pictogramsGHS hazard pictograms
注意喚起語 警告
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H302 飲み込むと有害 急性毒性、経口 4 警告 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 皮膚に接触すると有害 急性毒性、経皮 4 警告 GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 吸入すると有害 急性毒性、吸入 4 警告 GHS hazard pictograms P261, P271, P304+P340, P312
H351 発がんのおそれの疑い 発がん性 2 警告 P201, P202, P281, P308+P313, P405,P501
注意書き
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。

副腎皮質刺激ホルモン FROM PORCINE PITUITARY 価格 もっと(4)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan A6303 副腎皮質刺激ホルモン from porcine pituitary powder, 80-95?IU/mg (USP Corticotropin Ascorbic Acid Assay)
Adrenocorticotropic Hormone from porcine pituitary powder, 80-95?IU/mg (USP Corticotropin Ascorbic Acid Assay)		 9061-27-2 100iu ￥12900 2018-12-25 購入
Sigma-Aldrich Japan A6303 副腎皮質刺激ホルモン from porcine pituitary powder, 80-95?IU/mg (USP Corticotropin Ascorbic Acid Assay)
Adrenocorticotropic Hormone from porcine pituitary powder, 80-95?IU/mg (USP Corticotropin Ascorbic Acid Assay)		 9061-27-2 250iu ￥21600 2018-12-25 購入
Sigma-Aldrich Japan A6303 副腎皮質刺激ホルモン from porcine pituitary powder, 80-95?IU/mg (USP Corticotropin Ascorbic Acid Assay)
Adrenocorticotropic Hormone from porcine pituitary powder, 80-95?IU/mg (USP Corticotropin Ascorbic Acid Assay)		 9061-27-2 1000iu ￥61000 2018-12-25 購入
Sigma-Aldrich Japan A6303 副腎皮質刺激ホルモン from porcine pituitary powder, 80-95?IU/mg (USP Corticotropin Ascorbic Acid Assay)
Adrenocorticotropic Hormone from porcine pituitary powder, 80-95?IU/mg (USP Corticotropin Ascorbic Acid Assay)		 9061-27-2 5000iu ￥232800 2018-12-25 購入

副腎皮質刺激ホルモン FROM PORCINE PITUITARY 化学特性,用途語,生産方法

適応症

Adrenocorticotropic hormone (ACTH), or corticotropin, a peptide of 39 amino acids, is first synthesized as a larger precursor from which ACTH is derived by proteolytic cleavage. ACTH stimulates production of glucocorticoids from the adrenal cortex. Release of ACTH depends on diurnal rhythms with serum levels highest in the early morning. Secretion of this peptide also increases under stress. It is easier and less expensive to treat patients having adrenocortical insufficiency with glucocorticoid replacement therapy than it is to use ACTH. Therefore, use of ACTH (Acthar) is restricted to diagnosis; a shorter 24–amino acid analogue (Cosyntropin) is also used. Intravenous administration of ACTH should result in peak plasma levels of glucocorticoids within 30 to 60 minutes if the adrenal gland is functional. Prolonged administration of ACTH in a repository form, however, may be necessary to stimulate steroid production, because ACTH has long-term trophic effects on adrenal cells in addition to the rapid stimulation of steroid production. If the cause of steroid deficiency is at the level of the pituitary gland, ACTH should eventually stimulate steroid production.

生物学の機能

The main function of Adrenocorticotropic hormone (ACTH) is to regulate the glucocorticoid (steroid) hormone cortisol. Cortisol is released by the adrenal gland. It regulates blood pressure, blood sugar, the immune system, and the response to stress. This test can help find the causes of certain hormone problems

健康ハザード

Adrenocorticotropic Hormone (ACTH;Adrenocorticotropin; corticotropic hormone): (1)Maintenance of adrenal cortex;(2)Promotes secretion of steroids, oxidative phosphorylation in adrenal cortex;(3)Mobilizes and increases oxidation of free fatty acid in adipose tissue;(4)Increases gluconeogenesis in liver; increases cyclic adenosine monophosphate (AMP) in adrenal cortex;Decreases urea formation in liver.

Biochem/physiol Actions

Stimulates synthesis and secretion of glucocorticoids by adrenal cortex.

副腎皮質刺激ホルモン FROM PORCINE PITUITARY 上流と下流の製品情報

原材料

準備製品

副腎皮質刺激ホルモン FROM PORCINE PITUITARY 生産企業

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9061-27-2(副腎皮質刺激ホルモン FROM PORCINE PITUITARY)キーワード:

α-メラノトロピン アドレノコルチコトロピン コートロシン 副腎皮質刺激ホルモン (1-39), ヒト フッ化ケイ素酸 L-Ser-L-Tyr-L-Ser-L-Met-L-Glu-L-His-L-Phe-L-Arg-L-Trp-Gly-L-Lys-L-Pro-L-Val-Gly-L-Lys-L-Lys-OH L-Lys-L-Pro-L-Val-Gly-L-Lys-L-Lys-L-Arg-L-Arg-L-Pro-L-Val-L-Lys-L-Val-L-Tyr-L-Pro-OH 副腎皮質刺激ホルモンフラグメント 1-17 ヒト, ラット ACTH(1-13)【ヒト】 副腎皮質刺激ホルモン (1-39), ラット ACTH(4-9) 副腎皮質刺激ホルモン (4-10), HUMAN PROTEOMASS™ACTHフラグメント18-39 MALDI-MSスタンダード L-Glu-L-His-L-Phe-L-Arg-L-Trp-Gly-OH
  • 9061-27-2
  • adrenocorticotropic hormone from*porcine pituitar
  • alpha1-39-Corticotropin (pig)
  • ADRENOCORTICOTROPIC HORMONE FROM PORCINE PITUITARY
  • AdrenocorticotrophicHormone,Porcine
  • Adrenocorticotropic Hormone Fragment 1-39, Corticotropin A
  • PORCINE ADRENOCORTICOTROPIC HORMONE
  • CORTICOTROPIN A
  • ACTH 1-39
  • ACTH (1-39), PORCINE
  • ADRENOCORTICOTROPIC HORMONE
  • ADRENOCORTICOTROPIC HORMONE, PORCINE
  • ADRENOCORTICOTROPIC HORMONE PORCINE PITUITARY
  • ADRENOCORTICOTROPIC HORMONE
  • 副腎皮質刺激ホルモン FROM PORCINE PITUITARY
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