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N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine

化学構造式
1246298-48-5
CAS番号.
1246298-48-5
化学名:
别名:
英語名:
N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
英語别名:
20:0(2S-OH) Ceramide;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine;N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE;Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
CBNumber:
CB42719825
化学式:
C38H75NO4
分子量:
610.01
MOL File:
1246298-48-5.mol

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine 物理性質

沸点 :
739.3±60.0 °C(Predicted)
比重(密度) :
0.939±0.06 g/cm3(Predicted)
貯蔵温度 :
-20°C
酸解離定数(Pka):
13.26±0.20(Predicted)

安全性情報

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine 価格 もっと(1)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan 860820P N-(2′-(S)-hydroxyarachidoyl)-D-erythro-sphingosine, powder
20:0(2S-OH) Ceramide N-(2′-(S)-hydroxyarachidoyl)-D-erythro-sphingosine, powder		 1246298-48-5 5mg ￥79700 2024-03-01 購入

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine 化学特性,用途語,生産方法

一般的な説明

Ceramides linked to 2-hydroxy fatty acids (hFA) are present in the surface epithelium of the skin. 20:0(2S-OH) Ceramide is a unique ceramide containing 20C long chain base fatty acid (arachidic acid)-with 2′-hydroxyl group in S configuration.

Biochem/physiol Actions

Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an?antitumor drug to exhibit its activity.

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine 上流と下流の製品情報

原材料

準備製品

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine 生産企業

Global( 6)Suppliers
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 amy@howeipharm.com China 17698 55
Chengdu Dianchun Technology Co., Ltd 400-1166-196 18502815961
 cdhxsj@163.com China 14623 60
  • 1246298-48-5
  • N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
  • 20:0(2S-OH) Ceramide
  • N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE
  • Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
  • N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
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