2,2,4-トリメチル-1,3-ペンタンジオール 化学特性,用途語,生産方法
外観
白色~わずかにうすい黄色, 結晶性粉末又は塊
溶解性
エタノール及びアセトンに溶け、水にわずかに溶ける。
化学的特性
2,2,4-Trimethyl-1,3-pentanediol is a somewhat volatile liquid.
使用
Main uses of 2,2,4-Trimethyl-1,3-pentanediol are as a
component of polyester resins used in food packaging and as an insect repellent. Industrial exposure is likely to be by
direct contact with the liquid. Vapors or mists may be
encountered under some conditions.
調製方法
2,2,4-Trimethyl-1,3-pentanediol is made by reacting isobutyryl
chloride with ethyl isobutyrate.
定義
2,2,4-Trimethyl-1,3-pentanediol (TMPD) glycol, with one primary and one secondary hydroxyl function, shows the typical reactivity of a diol. In comparison to other diols, such as 1,4-cyclohexanedimethanol) or NPG (Neopentyl glycol), TMPD glycol has an unsymmetrical structure and shielded hydroxyl groups.
毒性学
2,2,4-trimethyl-1,3-pentanediol (TMPD Glycol) is classified as "slightly toxic". In rabbits, moderate eye irritation was observed. Slight to no skin irritation occurred in guinea pigs, and no skin sensitization was found. Repeated skin application studies in humans gave no evidence of irritation, sensitization, photosensitization, or systemic toxic effects. In humans, TMPD glycol is rapidly excreted in the urine, partly unchanged, partly as the glucuronide and sulfate conjugates, and partly as 2,2,4-trimethyl-3-hydroxyvaleric acid. LD50 2000 (rat, oral), LD50 145 (rat, intravenous).
2,2,4-トリメチル-1,3-ペンタンジオール 上流と下流の製品情報
原材料
3-ヒドロキシ-2,2,4-トリメチルバレルアルデヒド
2,4-ジイソプロピル-5,5-ジメチル-1,3-ジオキサン-6-オール
3-Pentanone, 1-hydroxy-2,2,4-trimethyl-
3-hydroxy-2,2,4,4-tetramethylcyclobutan-1-one
2,4-ジメチル-3-ペンタノール
イソ酪酸2,2,4-トリメチル-3-ヒドロキシペンチル
テトラメチル-1,3-シクロブタンジオン
イソ酪酸 クロリド
準備製品