2,2,4-Trimethylpentan-1,3-diol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
2,2,4-Trimethyl-1,3-pentanediol is a somewhat volatile liquid.
Verwenden
Main uses of 2,2,4-Trimethyl-1,3-pentanediol are as a
component of polyester resins used in food packaging and as an insect repellent. Industrial exposure is likely to be by
direct contact with the liquid. Vapors or mists may be
encountered under some conditions.
Vorbereitung Methode
2,2,4-Trimethyl-1,3-pentanediol is made by reacting isobutyryl
chloride with ethyl isobutyrate.
Definition
2,2,4-Trimethyl-1,3-pentanediol (TMPD) glycol, with one primary and one secondary hydroxyl function, shows the typical reactivity of a diol. In comparison to other diols, such as 1,4-cyclohexanedimethanol) or NPG (Neopentyl glycol), TMPD glycol has an unsymmetrical structure and shielded hydroxyl groups.
Toxikologie
2,2,4-trimethyl-1,3-pentanediol (TMPD Glycol) is classified as "slightly toxic". In rabbits, moderate eye irritation was observed. Slight to no skin irritation occurred in guinea pigs, and no skin sensitization was found. Repeated skin application studies in humans gave no evidence of irritation, sensitization, photosensitization, or systemic toxic effects. In humans, TMPD glycol is rapidly excreted in the urine, partly unchanged, partly as the glucuronide and sulfate conjugates, and partly as 2,2,4-trimethyl-3-hydroxyvaleric acid. LD50 2000 (rat, oral), LD50 145 (rat, intravenous).
2,2,4-Trimethylpentan-1,3-diol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
3-Hydroxy-2,2,4-trimethylvaleraldehyde
2,6-Diisopropyl-5,5-dimethyl-1,3-dioxan-4-ol
3-Pentanone, 1-hydroxy-2,2,4-trimethyl-
3-hydroxy-2,2,4,4-tetramethylcyclobutan-1-one
2,4-Dimethylpentan-3-ol
3-Hydroxy-2,2,4-trimethylpentylisobutyrat
Tetramethylcyclobutan-1,3-dion
Downstream Produkte
