UPCDC30245
UPCDC30245 物理性質
- 沸点 :
- 647.6±55.0 °C(Predicted)
- 比重(密度) :
- 1.20±0.1 g/cm3(Predicted)
- 貯蔵温度 :
- 2-8°C
- 酸解離定数(Pka):
- 16.22±0.30(Predicted)
- 外見 :
- 粉
- 色:
- 白からベージュ
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
UPCDC30245 価格
もっと(2)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
SML1674 |
≥98% (HPLC)
UPCDC30245 ≥98% (HPLC) |
1883351-01-6 |
5mg |
￥26500 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
SML1674 |
≥98% (HPLC)
UPCDC30245 ≥98% (HPLC) |
1883351-01-6 |
25mg |
￥84500 |
2024-03-01 |
購入 |
UPCDC30245 化学特性,用途語,生産方法
Biochem/physiol Actions
UPCDC30245 is an allosteric inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). p97 is an integral component of the ubiquitin fusion degradation (UFD) pathway. It plays a role in degradation of misfolded proteins, Golgi membrane reassembly, membrane transport, myofibril assembly, autophagosome maturation, and cell division, and is overexpressed in many tumor types. UPCDC30245 has an IC50 value of 27 nM, and has been shown to bind at the junction between the D1 and D2 domains of p97. UPCDC30245 has been used in cryo-ECM to show how such inhibitor binding prevents the confomational changes necessary for p97 function.
UPCDC30245 上流と下流の製品情報
原材料
準備製品
UPCDC30245 生産企業
Global( 9)Suppliers
- 1883351-01-6
- UPCDC30245
- UPCDC30245 >=98% (HPLC)
- 1-Piperazineethanamine, N-[1-[3-(5-fluoro-1H-indol-2-yl)phenyl]-4-piperidinyl]-4-(1-methylethyl)-