GMDP

GMDP 価格

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GMDP 化学特性,用途語,生産方法

説明

N-acetyl-β-D-glucosaminyl-( 1→4)-N-acetylmuramyl-L-alanyl-D-isoglutamine was launched in Russia for hospital-related infections, psoriasis, cervical precancerous lesions and ophthalmic keratitis caused by herpes. It was found to be less pyrogenic than MDP, the minimally active component of Freund's complete adjuvant. While chemical synthesis is possible, a less laborious method (3 steps) involves the enzymatic degradation of a bacterial peptidoglycan. GDMP is orally active with a low toxicity that acts as an adjuvant to highly purified protein antigens to stimulate the induction of CD8^* T-cell response. It was also able to reduce the levels of TNF-α, IL-1α and hypoglycemia induced by LPS administration and to inhibit systemic response to endotoxin.

Originator

Peptech (Australia)

brand name

Likopid

GMDP 上流と下流の製品情報

原材料

準備製品

GMDP 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Nanjing Peptide Biotech Ltd.	025-58361106-805 13082558573	liugang@njpeptide.com	China	9961	55
Nantong Hanfang Biotechnology Co. , Ltd.	3674309880	hanfangpharma@126.com	China	30968	58

70280-03-4(GMDP)キーワード:

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• 70280-03-4
• d-alpha-glutamine,n-(n-acetyl-4-o-(2-(acetylamino)-2-deoxy-beta-d-glucopyrano
• glucosaminylmuramyldipeptide
• n-acetyl-beta-glucosaminyl-(1-4)-n-acetylmuramyl-l-alanyl-d-isoglutamine
• n-acetyl-beta-glucosaminyl-n-acetylmuramyl-alanylisoglutamine
• n-acetylglucosaminyl-n-acetylmuramyl-l-alanyl-d-isoglutamine
• syl)muramoyl)-l-alanyl-
• 4-(2-acetamido-2-deoxy-B-D-*glucopyranosyl)-N-ace
• N-Acetyl-D-glucosaminyl-(b1,4)-N-acetylmuramyl-L-alanyl-D-io
• 4-(2-ACETAMIDO-2-DEOXY-B-D- &
• 4-(2-acetamido-2-deoxy-β-d-glucopyranosyl)-n-acetylmuramyl-l-ala-d-glu amide
• d-glcnac-β-(1→4)-n-acetylmuramyl-l-ala-d-isoglutamine
• D-GLCNAC-BETA-(1->4)-N-ACETYLMURAMYL-L-ALA-D-ISOGLUTAMINE
• GMDP
• N-ACETYL-D-GLUCOSAMINYL-(BETA1,4)-N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE
• 4-(2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSYL)-N-ACETYLMURAMYL-L-ALA-D-GLU AMIDE
• N-Acetyl-beta-D-Glucosaminyl-N-Acetylmuramyl-L-Alanyl-D-Isoglutamine
• D-α-Glutamine, N-[N-acetyl-4-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]muramoyl]-L-alanyl-
• (4R)-4-((2S)-2-((2R)-2-(((3R,4R,5S,6R)-3-acetamido-5-(((2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)propanamido)propanamido)-5-amino-5-oxopentanoic acid
• N-?Acetyl-?β-?D-?glucosaminyl-?N-?acetylmuramyl-?L-?alanyl-?D-?isoglutamine
• (4R)-4-カルバモイル-4-[(2S)-2-[(2R)-2-{[(3R,4R,5S,6R)-3-アセトアミド-5-{[(2S,3R,4R,5S,6R)-3-アセトアミド-4,5-ジヒドロキシ-6-(ヒドロキシメチル)オキサン-2-イル]オキシ}-2-ヒドロキシ-6-(ヒドロキシメチル)オキサン-4-イル]オキシ}プロパンアミド]プロパンアミド]ブタン酸
• N2-[N-[4-O-(2-アセチルアミノ-2-デオキシ-β-D-グルコピラノシル)-N-アセチルムラモイル]-L-Ala-]-D-αGln-OH
• GMDP
• N-[N-アセチル-4-O-[2-(アセチルアミノ)-2-デオキシ-β-D-グルコピラノシル]ムラモイル]-L-Ala-D-Glu-NH2