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IVACHTIN

化学構造式
745046-84-8
CAS番号.
745046-84-8
化学名:
别名:
英語名:
IVACHTIN
英語别名:
IVACHTIN;2-(4-methyl-8-morpholin-4-ylsulfonyl-1,3-dioxopyrrolo[3,4-c]quinolin-2-yl)ethyl acetate;1H-Pyrrolo[3,4-c]quinoline-1,3(2H)-dione, 2-[2-(acetyloxy)ethyl]-4-methyl-8-(4-morpholinylsulfonyl)-;2-[4-Methyl-8-(morpholin-4-ylsulfonyl)-1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]quinolin-2-yl]ethylacetate;modest,reversibl,Inhibitor,noncompetitive,Caspase,caspases,nonpeptide,inhibit,apoptosis,Ivachtin,selectivity,staurosporininduced
CBNumber:
CB82459565
化学式:
C20H21N3O7S
分子量:
447.46
MOL File:
745046-84-8.mol

IVACHTIN 物理性質

沸点 :
665.0±65.0 °C(Predicted)
比重(密度) :
1.459±0.06 g/cm3(Predicted)
貯蔵温度 :
Desiccate at +4°C
溶解性:
Limited solubility, soluble in DMSO or DMF
酸解離定数(Pka):
1.87±0.20(Predicted)
外見 :
オフホワイトの無地

安全性情報

IVACHTIN 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

IVACHTIN 化学特性,用途語,生産方法

使用

Ivachtin is a potent, cell-permeable, reversible, non-competitive inhibitor of caspase-3.

一般的な説明

A cell-permeable, non-peptidyl pyrroloquinoline compound that acts as a potent, reversible, and non-competitive inhibitor of caspase-3 (IC50 = 23 nM) with larger than 10-fold greater selectivity towards caspase-3 than caspases-1, -2, and -4 through -10. Shown to display higher anti-apoptotic activity than Z-VAD-FMK (Cat. No. 627610) in preventing Staurosporine- (Cat. No. 569397) induced apoptosis in human Jurkat T cells.

Biochem/physiol Actions

Cell permeable: yes

IVACHTIN 上流と下流の製品情報

原材料

準備製品

IVACHTIN 生産企業

Global( 53)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894
 shawn@hirisunpharm.com CHINA 9923 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15848 69
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 14059 65
AdooQ BioScience, LLC +1 (866) 930-6790
info@adooq.com United States 2784 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9709 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720
 psaitong@jm-bio.com China 12308 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029
synstar518@163.com China 1991 58

  スペクトルデータ(1HNMR)

IVACHTIN(745046-84-8)1HNMR

745046-84-8()キーワード:

4-メチル-1H-ピロロ[3,4-C]キノリン-1,3(2H)-ジオン 酢酸2-(3-ピリジニルカルボニルアミノ)エチル
  • 745046-84-8
  • IVACHTIN
  • 2-[4-Methyl-8-(morpholin-4-ylsulfonyl)-1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]quinolin-2-yl]ethylacetate
  • 2-(4-methyl-8-morpholin-4-ylsulfonyl-1,3-dioxopyrrolo[3,4-c]quinolin-2-yl)ethyl acetate
  • modest,reversibl,Inhibitor,noncompetitive,Caspase,caspases,nonpeptide,inhibit,apoptosis,Ivachtin,selectivity,staurosporininduced
  • 1H-Pyrrolo[3,4-c]quinoline-1,3(2H)-dione, 2-[2-(acetyloxy)ethyl]-4-methyl-8-(4-morpholinylsulfonyl)-
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