SR144528

SR144528 価格 もっと(6)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01TRCS684400	SR144528 SR 144528	192703-06-3	5mg	￥47600	2023-06-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCS684400	SR144528 SR 144528	192703-06-3	10mg	￥86900	2023-06-01	購入
Sigma-Aldrich Japan	SML1899	≥98% (HPLC) SR144528 ≥98% (HPLC)	192703-06-3	5mg	￥28300	2024-03-01	購入
Sigma-Aldrich Japan	SML1899	≥98% (HPLC) SR144528 ≥98% (HPLC)	192703-06-3	25mg	￥88600	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCS684400	SR144528 SR 144528	192703-06-3	25mg	￥208500	2023-06-01	購入

SR144528 化学特性,用途語,生産方法

説明

SR 144528 is a cannabinoid (CB) receptor 2 inverse agonist with K_i values ranging from 0.3 to 5.6 nM. It is selective for CB₂ over CB₁ receptors, where it has K_i values ranging from 305 to >10,000 nM. SR 144528 blocks the inhibitory effects of CP 55,940 on forskolin-induced adenylyl cyclase activity in CHO cells expressing hCB₂ (IC₅₀ = 10 nM) but not in cells expressing hCB₁ (IC₅₀ = >10 μM). SR 144528 has been used to investigate the contribution of the CB₂ receptor in the control of pain initiation as well as suppression of inflammation and immune activation.

使用

SR 144528 acts as a selective peripheral cannabinoid (CB2) receptor inverse agonist. Used in studies involving application of cannibis and anticancer drugs and multi-drug resistance (MDR) of the patie nt.

Biochem/physiol Actions

SR144528 is a potent and highly selective cannabinoid CB2 receptor inverse agonist. SR144528 exhibited a Ki of 0.6 nM at CB2 compared to 400 nM at the related CB1 receptor.

SR144528 上流と下流の製品情報

原材料

準備製品

SR144528 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Wuhan Topule	+86-02787215551 +86-19945035818	2936752263@qq.com	China	7952	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65

192703-06-3(SR144528)キーワード:

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• 192703-06-3
• SR 144528
• 5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide
• 1H-Pyrazole-3-carboxamide, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-
• SR-144528,SR144528
• SR144528
• N-[(1S,2S,4R)-1,3,3-トリメチルビシクロ[2.2.1]ヘプタン-2-イル]-1-(4-メチルベンジル)-5-(3-メチル-4-クロロフェニル)-1H-ピラゾール-3-カルボアミド
• 5-(4-クロロ-3-メチルフェニル)-1-[(4-メチルフェニル)メチル]-N-[(1S,2S,4R)-1,3,3-トリメチルビシクロ[2.2.1]ヘプタン-2-イル]-1H-ピラゾール-3-カルボキサミド
• N-[(1S,4β)-1,3,3-トリメチルビシクロ[2.2.1]ヘプタン-2α-イル]-1-(4-メチルベンジル)-5-(3-メチル-4-クロロフェニル)-1H-ピラゾール-3-カルボアミド
• SR-144528