エリスロポイエチン 化学特性,用途語,生産方法
解説
エリスロポイエチン,《「エリスロポエチン」とも》腎臓で放出される赤血球増多作用のあるホルモン。低酸素状態になると放出される。人工的に合成したものは医薬品として利用する。EPO。
説明
Recombinant erythropoietin (EPO) is currently indicated for use only in anemia associated with renal transplant or end-stage renal disease. Widened indications for use in other forms of anemia, accompanied by price reductions as a result of keen competition, have been projected for EPO in the future.
使用
Erythropoietin can be used in biological study of its attenuation of cardiac dysfunction in rats by inhibiting endoplasmic reticulum stress-induced diabetic cardiomyopathy.
一般的な説明
EPO has been cloned from various species including human, murine, canine, and others. The mature proteins from the various species are highly conserved and exhibit greater than 80% amino acid sequence identity. EPO contains three N-linked glycosylation sites. The glycosylation of erythropoietin is required for the biological activities of erythropoietin in vivo.
エリスロポイエチン 上流と下流の製品情報
原材料
準備製品