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Dolutegravir Impurity 8

化学構造式
2244161-72-4
CAS番号.
2244161-72-4
化学名:
别名:
英語名:
Dolutegravir Impurity 8
英語别名:
Dolutegravir Impurity 59;2,6-Di fluoro Dolutegravir;Dolutegravir 2,6-difluoro Impurity;2,6 Difluoro dolutegravir sodium salt;1-Piperazinepropanenitrile,4-(2-methoxyphenyl)-;Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity);4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir;(4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber:
CB88117623
化学式:
C20H19F2N3O5
分子量:
419.38
MOL File:
2244161-72-4.mol

Dolutegravir Impurity 8 物理性質

沸点 :
664.9±55.0 °C(Predicted)
比重(密度) :
1.53±0.1 g/cm3(Predicted)
酸解離定数(Pka):
4.50±1.00(Predicted)

安全性情報

Dolutegravir Impurity 8 価格

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Dolutegravir Impurity 8 化学特性,用途語,生産方法

使用

4-Desfluoro-6-fluoro Dolutegravir is impurity C of Dolutegravir (D528800), which is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir Impurity 8 上流と下流の製品情報

原材料

準備製品

Dolutegravir Impurity 8 生産企業

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  • 2244161-72-4
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,6-difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
  • 2,6-Di fluoro Dolutegravir
  • Dolutegravir 2,6-Difluoro Analog (Dolutegravir 4-Desfluoro 6-Fluoro Impurity)
  • 4-Desfluoro-6-fluoro DolutegravirQ: What is 4-Desfluoro-6-fluoro Dolutegravir Q: What is the CAS Number of 4-Desfluoro-6-fluoro Dolutegravir
  • 2,6 Difluoro dolutegravir sodium salt
  • (4R,12aS)-N-(2,6-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
  • Dolutegravir 2,6-difluoro Impurity
  • Dolutegravir Impurity 59
  • 1-Piperazinepropanenitrile,4-(2-methoxyphenyl)-
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