Dolutegravir 4-Desfluoro Impurity
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- CAS番号.
- 1863916-87-3
- 化学名:
- 别名:
- 英語名:
- Dolutegravir 4-Desfluoro Impurity
- 英語别名:
- Dotiravir Impurity 2;Dotiravir Impurity 8;2-Fluoro Dolutegravir;4-Defluoro Dolutegravir;Dolutegravir Impurity 49;Dolutegravir Impurity 46;Doultegravir 2-F Impurity C;Dolutegravir 2-Fluoro Impurity;Dolutegravir Impurity C (4-Defluoro Dolutegravir);(4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- CBNumber:
- CB94796146
- 化学式:
- C20H20FN3O5
- 分子量:
- 401.39
- MOL File:
- 1863916-87-3.mol
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Dolutegravir 4-Desfluoro Impurity 物理性質
- 沸点 :
- 671.6±55.0 °C(Predicted)
- 比重(密度) :
- 1.49±0.1 g/cm3(Predicted)
- 酸解離定数(Pka):
- 4.50±1.00(Predicted)
安全性情報
Dolutegravir 4-Desfluoro Impurity 価格
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Dolutegravir 4-Desfluoro Impurity 化学特性,用途語,生産方法
使用
4-Defluro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dolutegravir 4-Desfluoro Impurity 上流と下流の製品情報
原材料
準備製品
Dolutegravir 4-Desfluoro Impurity 生産企業
Global( 35)Suppliers
1863916-87-3()キーワード:
- 1863916-87-3
- Dolutegravir impurity 1/4-Defluoro Dolutegravir/(4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- (4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
- 4-Defluoro Dolutegravir
- 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
- Doultegravir 2-F Impurity C
- Dolutegravir Impurity C (4-Defluoro Dolutegravir)
- Dolutegravir Impurity 46
- Dolutegravir Impurity 49
- 2-Fluoro Dolutegravir
- Dolutegravir 2-Fluoro Impurity
- Dotiravir Impurity 2
- Dotiravir Impurity 8