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Dolutegravir 4-Desfluoro Impurity

1863916-87-3

CAS-Nr.: 1863916-87-3

Englisch Name:: Dolutegravir 4-Desfluoro Impurity

Synonyma:: Dotiravir Impurity 2;Dotiravir Impurity 8;2-Fluoro Dolutegravir;4-Defluoro Dolutegravir;Dolutegravir Impurity 49;Dolutegravir Impurity 46;Doultegravir 2-F Impurity C;Dolutegravir 2-Fluoro Impurity;Dolutegravir Impurity C (4-Defluoro Dolutegravir);(4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

CBNumber:: CB94796146

Summenformel:: C20H20FN3O5

Molgewicht:: 401.39

MOL-Datei:: 1863916-87-3.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 35

Dolutegravir 4-Desfluoro Impurity Eigenschaften

Siedepunkt:: 671.6±55.0 °C(Predicted)

Dichte: 1.49±0.1 g/cm3(Predicted)

pka: 4.50±1.00(Predicted)

Sicherheit

Dolutegravir 4-Desfluoro Impurity Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

4-Defluro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 4-Desfluoro Impurity Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dolutegravir 4-Desfluoro Impurity Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 35)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
CR Corporation Lomited		fred.wen@crcorporation.cn	CHINA	12069	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12382	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8613627253706	sale@hdimpurity.com	China	1663	58
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-52878169 15701683040	sales@bjcomparison.com	China	4683	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17982	56
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Hubei Yangxin Medical Technology Co., Ltd.	15374522761	3003392093@qq.com	China	7851	55
Shanghai CR Corporation Limited	4006653949	fred.wen@crcorporation.cn	China	10108	58

Dolutegravir impurity 1/4-Defluoro Dolutegravir/(4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
(4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
4-Defluoro Dolutegravir
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
Doultegravir 2-F Impurity C
Dolutegravir Impurity C (4-Defluoro Dolutegravir)
Dolutegravir Impurity 46
Dolutegravir Impurity 49
2-Fluoro Dolutegravir
Dolutegravir 2-Fluoro Impurity
Dotiravir Impurity 2
Dotiravir Impurity 8
1863916-87-3