Piperazinone, 3-(2-thienyl)- (9CI)
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Piperazinone, 3-(2-thienyl)- (9CI) 속성
- 밀도
- 1.225
- InChI
- InChI=1S/C8H10N2OS/c11-8-7(9-3-4-10-8)6-2-1-5-12-6/h1-2,5,7,9H,3-4H2,(H,10,11)
- InChIKey
- BBACKDMGYMXYLE-UHFFFAOYSA-N
- SMILES
- N1CCNC(C2SC=CC=2)C1=O
안전
Piperazinone, 3-(2-thienyl)- (9CI) C화학적 특성, 용도, 생산
개요
Tenilsetam ((+/-)-3-(2-thienyl)-2-piperazinone; Piperazinone, 3-(2-thienyl)- (9CI)), a cognition-enhancing drug successfully used for the treatment of patients suffering from Alzheimer's disease, when included in the Maillard reaction inhibits protein crosslinking by AGEs in vitro. According to the mechanism proposed, Tenilsetam acts via covalent attachment to glycated proteins, thus blocking the reactive sites for further polymerisation reactions. A beneficial effect of Tenilsetam in Alzheimer's disease could come from the interference with AGE-derived crosslinking of amyloid plaques and a decreased inflammatory response by diminished activation of phagocytosing microglia[1].Piperazinone, 3-(2-thienyl)- (9CI) 준비 용품 및 원자재
원자재
준비 용품
Piperazinone, 3-(2-thienyl)- (9CI) 공급 업체
글로벌( 18)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29823 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 24099 | 58 |
| Wuhan Han Sheng New Material Technology Co.，Ltd | +8617798174412 |
admin01@hsnm.com.cn | China | 2118 | 58 |
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 |
sales@anbuchem.com | China | 3000 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 |
info@chemextension.com | China | 42057 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9707 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 |
info@amateksci.com | China | 28817 | 58 |
| BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
| Shanghai Haohong Scientific Co., Ltd. | 400-400-8210725 |
malulu@leyan.com | China | 39990 | 58 |