Piperazinone, 3-(2-thienyl)- (9CI)

Piperazinone, 3-(2-thienyl)- (9CI) 구조식 이미지
카스 번호:
86696-86-8
상품명:
Piperazinone, 3-(2-thienyl)- (9CI)
동의어(영문):
Tenilsetam;3-(2-thienyl)- (9CI);Tenilsetam/Piperazinone;3-(2-Thienyl)-2-piperazinone;3-(2-Thienyl)piperazin-2-one;2-Piperazinone, 3-(2-thienyl)-;Piperazinone, 3-(2-thienyl)- (9CI);Tenilsetam - PAS 997 | CAS 997 | HR 029;Piperazinone, 3-(2-thienyl)- (9CI) USP/EP/BP
CBNumber:
CB01052655
분자식:
C8H10N2OS
포뮬러 무게:
182.24
MOL 파일:
86696-86-8.mol

Piperazinone, 3-(2-thienyl)- (9CI) 속성

밀도
1.225
InChI
InChI=1S/C8H10N2OS/c11-8-7(9-3-4-10-8)6-2-1-5-12-6/h1-2,5,7,9H,3-4H2,(H,10,11)
InChIKey
BBACKDMGYMXYLE-UHFFFAOYSA-N
SMILES
N1CCNC(C2SC=CC=2)C1=O

안전

Piperazinone, 3-(2-thienyl)- (9CI) C화학적 특성, 용도, 생산

개요

Tenilsetam ((+/-)-3-(2-thienyl)-2-piperazinone; Piperazinone, 3-(2-thienyl)- (9CI)), a cognition-enhancing drug successfully used for the treatment of patients suffering from Alzheimer's disease, when included in the Maillard reaction inhibits protein crosslinking by AGEs in vitro. According to the mechanism proposed, Tenilsetam acts via covalent attachment to glycated proteins, thus blocking the reactive sites for further polymerisation reactions. A beneficial effect of Tenilsetam in Alzheimer's disease could come from the interference with AGE-derived crosslinking of amyloid plaques and a decreased inflammatory response by diminished activation of phagocytosing microglia[1].

Piperazinone, 3-(2-thienyl)- (9CI) 준비 용품 및 원자재

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준비 용품


Piperazinone, 3-(2-thienyl)- (9CI) 공급 업체

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