ascochlorin

ascochlorin 구조식 이미지
카스 번호:
26166-39-2
상품명:
ascochlorin
동의어(영문):
Nsc 287492;ascochlorin;Ilicicolin D;Ll-Z 1272 gamma;Antibiotics LL-Z 1272g;Antibiotic ll-Z1272 gamma;LL-Z 1272 gaMMa, Ilicicolin D;beta-Resorcylaldehyde, 5-chloro-6-methyl-3-(3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)-2,4-pentadienyl)-, (E,E)-;5-Chloro-2,4-dihydroxy-6-methyl-3-[(2E,4Z)-3-methyl-5-(1,2,6-trimethyl-3-oxocyclohexyl)penta-2,4-dienyl]benzaldehyde;3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,4E)-3-methyl-5-[(1R)-1β,2β,6β-trimethyl-3-oxocyclohexyl]-2,4-pentadienyl]benzaldehyde
CBNumber:
CB01364846
분자식:
C23H29ClO4
포뮬러 무게:
404.931
MOL 파일:
26166-39-2.mol

ascochlorin 속성

녹는점
172-174 °C
끓는 점
556.9±39.0 °C(Predicted)
밀도
1.199±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMSO: 용해될 수 있다
물리적 상태
분말
산도 계수 (pKa)
6.26±0.50(Predicted)

안전

WGK 독일 3
독성 mouse,LD50,intraperitoneal,20mg/kg (20mg/kg),Journal of Antibiotics. Vol. 21, Pg. 539, 1968.

ascochlorin C화학적 특성, 용도, 생산

용도

Ascochlorin is an antitumor fungal metabolite which specifically inhibits matrix metalloproteinase-9 (MMP-9) activity through suppression of activator protein-1 (AP-1)-dependent induction of MMP-9 gene expression. Via AP-1 suppression, ascochlorin selectively kills MX-1 cells, a human breast cancer cell line lacking estrogen receptors. Ascochlorin also shows activity against Newcastle disease and herpes simplex viruses.

ascochlorin 준비 용품 및 원자재

원자재

준비 용품


ascochlorin 공급 업체

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