ANTI-HOGG1

ANTI-HOGG1 구조식 이미지
카스 번호:
상품명:
ANTI-HOGG1
동의어(영문):
Anti-Mmh;Anti-MUTM;Anti-HMMH;Anti-OGH1;ANTI-HOGG1;ANTI-OGG1 (HUMAN);Anti-8-oxoguanine DNA glycosylase;Anti-OGG1 antibody produced in goat;Anti-OGG1 antibody produced in mouse;Anti-OGG1 antibody produced in rabbit
CBNumber:
CB0193461
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

ANTI-HOGG1 속성

저장 조건
-20°C
물리적 상태
완충 수용액

안전

ANTI-HOGG1 C화학적 특성, 용도, 생산

일반 설명

This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. (provided by RefSeq)

Biochem/physiol Actions

The gene OGG1 (8-oxoguanine DNA glycosylase) is responsible for the excision of 8-oxoguanine, which is the most common form of oxidative DNA damage and is removed by the base excision repair pathway. OGG1 also has lyase activity that results in a single strand break. Variation in OGG1 (8-oxoguanine DNA glycosylase) is associated with age-related cataract and serves as a genetic biomarker in indicating the same.

ANTI-HOGG1 준비 용품 및 원자재

원자재

준비 용품


ANTI-HOGG1 공급 업체

글로벌( 7)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Riedel-de Haen AG --
United States 6825 87
Fluorochem Ltd --
vernam@fluorochem.co.uk United Kingdom 6383 65
Alexis Corporation --
alexis-ch@alexis-corp.ch Switzerland 3599 74
A.G. Scientific, Inc. --
support@agscientific.com United States 1066 71
Novus Biologicals, Inc. --
novus@novusbio.com United States 175 77
Fluorochem Ltd. --
enquiries@fluorochem.co.uk United Kingdom 6406 74
BIOTREND Chemikalien GmbH --
jaeger@biotrend.com Germany 6115 76

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