TCS 46B

TCS 46B 구조식 이미지
카스 번호:
302799-86-6
상품명:
TCS 46B
동의어(영문):
TCS 46B;1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]-
CBNumber:
CB02453446
분자식:
C22H23N3O
포뮬러 무게:
345.44
MOL 파일:
302799-86-6.mol

TCS 46B 속성

끓는 점
440.4±38.0 °C(Predicted)
밀도
1.24±0.1 g/cm3(Predicted)
저장 조건
Store at RT
용해도
Soluble to 100 mM in DMSO and to 100 mM in ethanol
물리적 상태
가루
산도 계수 (pKa)
11.51±0.30(Predicted)

안전

TCS 46B C화학적 특성, 용도, 생산

용도

TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist.

생물학적 활성

Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC 50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration.

TCS 46B 준비 용품 및 원자재

원자재

준비 용품


TCS 46B 공급 업체

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