(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 구조식 이미지
카스 번호:
1714114-25-6
상품명:
(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate
동의어(영문):
D-Alanine, N-[(S)-(2,3,4,5,6-pentafluorophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester;(S)-Isopropyl 2-(((R)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate (sofosbuvir Impurity)
CBNumber:
CB02715788
분자식:
C18H17F5NO5P
포뮬러 무게:
453.3
MOL 파일:
1714114-25-6.mol

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 속성

끓는 점
442.6±55.0 °C(Predicted)
밀도
1.405±0.06 g/cm3(Predicted)
산도 계수 (pKa)
-3.81±0.70(Predicted)

안전

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate C화학적 특성, 용도, 생산

용도

N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-D-alanine 1-Methylethyl Ester is an impurity of PSI-7977 (P839640); a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 준비 용품 및 원자재

원자재

준비 용품


(R)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)aMino)propanoate 공급 업체

글로벌( 11)공급 업체
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China National Standard Pharmaceutical Corporation Limited
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