ANTI A-CAM;MONOCLONAL ANTI-N-CADHERIN;ANTI-A-CELL ADHESION MOLECULE;Anti-A-CAM, Anti-A-Cell Adhesion Molecule;Monoclonal Anti-N-Cadherin antibody produced in mouse
Monoclonal anti-N-cadherin antibody can be used in immunohistochemistry (1: 100) and as primary antibody in western blotting (1:1000) .
일반 설명
N-cadherin is a calcium dependent cell adhesion molecule and is present mainly in cancer cells. Monoclonal anti-N-cadherin antibody reacts with the N-terminal portion of the extracellular domain of adipocyte adhesion molecule (ACAM).
Biochem/physiol Actions
N-cadherin regulates the Src kinase pathway and also promotes cell motility and invasion. It inhibits adherens junction formation and disrupts existing junctions of cultured lens cells.
