Rabbit anti-BRD4 Antibody, Affinity Purified

Rabbit anti-BRD4 Antibody, Affinity Purified 구조식 이미지
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상품명:
Rabbit anti-BRD4 Antibody, Affinity Purified
동의어(영문):
Rabbit anti-BRD4 Antibody, Affinity Purified
CBNumber:
CB12967616
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

Rabbit anti-BRD4 Antibody, Affinity Purified 속성

저장 조건
2-8°C

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Rabbit anti-BRD4 Antibody, Affinity Purified C화학적 특성, 용도, 생산

일반 설명

Bromodomain-containing protein 4 (BRD4) belongs to the bromodomain and extra-terminal (BET) family. The protein has two bromodomains (BD1 and BD2) connected by a long interdomain linker.

Biochem/physiol Actions

Bromodomain-containing protein 4 (BRD4) works as a reader of epigenetic marks and is involved in chromatin remodeling and transcriptional regulation. Therefore, it is a target for oncology, inflammation and cardiovascular disease. This gene is upregulated in hepatocellular carcinoma and is associated with poor prognosis. BRD4 is also associated with melanoma, hepatocellular carcinoma, multiple myeloma, Burkitt′s lymphoma, acute myeloid leukemia and breast cancer. BRD4 connects cell cycle and transcription, works as a scaffold for transcription factors and bookmarks active genes during mitosis. It interacts with acetylated histone-3 and histone-4 tails and helps in maintaining chromatin architecture. Also, it regulates transcription elongation via phosphorylation of RNA polymerase II.

Rabbit anti-BRD4 Antibody, Affinity Purified 준비 용품 및 원자재

원자재

준비 용품


Rabbit anti-BRD4 Antibody, Affinity Purified 공급 업체

글로벌( 6)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Shanghai Universal Biotech Co.,Ltd 18768175414
gaojun@univ-bio.com China 24998 58

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