HUMAN FGF-4

HUMAN FGF-4 구조식 이미지
카스 번호:
상품명:
HUMAN FGF-4
동의어(영문):
FGF-4;K-FGF;HST-1;HBGF-4;hFGF-4;HUMAN FGF-4;FGF-4, HUMAN;RECOMBINANT HUMAN FGF-4;transforming protein KS3;FIBROBLAST GROWTH FACTOR-4
CBNumber:
CB1372993
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

HUMAN FGF-4 속성

저장 조건
−20°C
물리적 상태
동결건조된 분말

안전

WGK 독일 3

HUMAN FGF-4 C화학적 특성, 용도, 생산

용도

Fibroblast Growth Factor-4 human has been used:
  • To maintain trophectoderm stem cells.
  • In neurogenic differentiation.
  • In hepatocyte differentiation.

일반 설명

Fibroblast Growth Factor-4 (FGF4) is a 19 kDa protein, belonging to the FGF family of proteins. Fibroblast growth factors (FGF) are glycoproteins concealed in the extracellular matrix and cell surface. There are around 22 different types of FGFs known. These factors weigh in the range of 17 to 34 kDa and they possess a conserved sequence of 120 amino acids. The FGF4 gene is mapped to human chromosome 11q13.3.

Biochem/physiol Actions

Fibroblast growth factor-4 (FGF-4) is identified in NIH-3T3 cell assays as a transforming gene from DNA derived from human tumors, including stomach (hst) and colon cancers, Kaposi′s sarcoma, and hepatocellular carcinoma. FGF-4 includes a secretory signal sequence and shares 42% sequence identity with FGF-Basic at the amino acid level. Both FGF-4 and FGF-Basic bind to the same receptors. Mouse and human FGF-4 shares 82% homology with species cross-reactivity. FGF-4 does not appear to be expressed in normal adult tissues, but during embryogenesis, the gene is spatially and temporally regulated. FGF-4 is a mitogen for fibroblasts and endothelial cells and a potent promoter of angiogenesis. It is believed to be critical in embryonic limb development. FGF-4 participates in cell differentiation and cell migration.

HUMAN FGF-4 준비 용품 및 원자재

원자재

준비 용품


HUMAN FGF-4 공급 업체

글로벌( 73)공급 업체
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BOC Sciences
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Sigma-Aldrich 021-61415566 800-8193336
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Creative Peptides
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Shanghai Kanglang Biotechnology Co., Ltd. 021-61998208 18217752821
sales@klbio.cn China 9618 58
Absin Bioscience Inc. 021-38015121 15000105423
wulan@absin.cn China 24734 58
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062
422450190@qq.com China 10351 58
Shanghai Yingxin Laboratory Equipment Co., Ltd. 021-021-59178156 17002132182
3146474380@qq.com China 11609 58
Biolab Reagents 027-65279366 18162686757
products@biolabreagent.com China 9818 58
Wuhan Peptide Core Biotechnology Co., Ltd 027-65317797 13667154760
1096814016@qq.com China 10056 58
ACROBiosystems 18514007688
jiaxin.zhao@acrobiosystems.com China 1002 58

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