HUMAN FGF-4

HUMAN FGF-4 C화학적 특성, 용도, 생산

용도

Fibroblast Growth Factor-4 human has been used:

• To maintain trophectoderm stem cells.
• In neurogenic differentiation.
• In hepatocyte differentiation.

일반 설명

Fibroblast Growth Factor-4 (FGF4) is a 19 kDa protein, belonging to the FGF family of proteins. Fibroblast growth factors (FGF) are glycoproteins concealed in the extracellular matrix and cell surface. There are around 22 different types of FGFs known. These factors weigh in the range of 17 to 34 kDa and they possess a conserved sequence of 120 amino acids. The FGF4 gene is mapped to human chromosome 11q13.3.

Biochem/physiol Actions

Fibroblast growth factor-4 (FGF-4) is identified in NIH-3T3 cell assays as a transforming gene from DNA derived from human tumors, including stomach (hst) and colon cancers, Kaposi′s sarcoma, and hepatocellular carcinoma. FGF-4 includes a secretory signal sequence and shares 42% sequence identity with FGF-Basic at the amino acid level. Both FGF-4 and FGF-Basic bind to the same receptors. Mouse and human FGF-4 shares 82% homology with species cross-reactivity. FGF-4 does not appear to be expressed in normal adult tissues, but during embryogenesis, the gene is spatially and temporally regulated. FGF-4 is a mitogen for fibroblasts and endothelial cells and a potent promoter of angiogenesis. It is believed to be critical in embryonic limb development. FGF-4 participates in cell differentiation and cell migration.

HUMAN FGF-4 준비 용품 및 원자재

원자재

준비 용품

HUMAN FGF-4 공급 업체

공급자	전화	이메일	국가	제품 수	이점
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19743	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Creative Peptides		info@creative-peptides.com	United States	6084	56
Shanghai Kanglang Biotechnology Co., Ltd.	021-61998208 18217752821	sales@klbio.cn	China	9618	58
Absin Bioscience Inc.	021-38015121 15000105423	wulan@absin.cn	China	24734	58
Wuhan Chemstan Biotechnology Co., Ltd.	027-65317797 15926423062	422450190@qq.com	China	10351	58
Shanghai Yingxin Laboratory Equipment Co., Ltd.	021-021-59178156 17002132182	3146474380@qq.com	China	11609	58
Biolab Reagents	027-65279366 18162686757	products@biolabreagent.com	China	9818	58
Wuhan Peptide Core Biotechnology Co., Ltd	027-65317797 13667154760	1096814016@qq.com	China	10056	58
ACROBiosystems	18514007688	jiaxin.zhao@acrobiosystems.com	China	1002	58