CINALUKAST

CINALUKAST 구조식 이미지
카스 번호:
128312-51-6
상품명:
CINALUKAST
동의어(영문):
Ro 24-591;RO 24-5913;CINALUKAST;C·Nalukast;2,2-Diethyl-N-[3-[(E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]succinamidic acid;(E)-4-[[3-(2-(4-CYCLOBUTYL-2-THIAZOLYL)ETHENYL)PHENYL]AMINO]-2,2-DIETHYL-4-OXOBUTANOIC ACID;4-[[3-[(1E)-2-(4-CYCLOBUTYL-2-THIAZOLYL)ETHENYL]PHENYL]AMINO]-2,2-DIETHYL-4-OXOBUTANOIC ACID;Butanoic acid, 4-[[3-[(1E)-2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]aMino]-2,2-diethyl-4-oxo-;Ro 24-5913, (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
CBNumber:
CB1486281
분자식:
C23H28N2O3S
포뮬러 무게:
412.55
MOL 파일:
128312-51-6.mol
MSDS 파일:
SDS

CINALUKAST 속성

저장 조건
2-8°C
용해도
DMSO: >10mg/mL
물리적 상태
가루
색상
회백색

안전

안전지침서 22-24/25
WGK 독일 3

CINALUKAST C화학적 특성, 용도, 생산

정의

ChEBI: 2,2-Diethylsuccinanilic acid substituted at a meta- position by an (E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl group. It selectively antagonizes leukotriene D4 at the cysteinyl leukotriene receptor, in th human airway, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. It is used in the treatment of asthma.

생물학적 활성

Potent, selective CysLT 1 (LTD 4 ) leukotriene receptor antagonist (IC 50 = 6.4 nM). Inhibits LTD 4 -induced bronchoconstriction in guinea pigs when administered intravenously, orally or by aerosol.

CINALUKAST 준비 용품 및 원자재

원자재

준비 용품


CINALUKAST 공급 업체

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