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Thalidomide-NH-CH2-COOH

Thalidomide-NH-CH2-COOH 구조식 이미지

카스 번호:: 927670-97-1

상품명:: Thalidomide-NH-CH2-COOH

동의어(영문):: Thalidomide-NH-CH2-COOH;6-dioxopiperidin-3-yl)-1;3-dioxoisoindolin-4-yl)glycine;3-dioxoisoindol-4-yl]amino]acetic acid;(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine;2-[[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]amino]acetic acid;Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;[(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)amino]acetic acid;inhibit,Ligands for E3 Ligase,E3 ligase-recruiting Moiety,Inhibitor,Thalidomide NH CH2 COOH,ThalidomideNHCH2COOH,cereblon,Thalidomide-NH-CH-2-COOH,CRBN,Thalidomide

CBNumber:: CB18197022

분자식:: C15H13N3O6

포뮬러 무게:: 331.28

MOL 파일:: 927670-97-1.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 25

Thalidomide-NH-CH2-COOH 속성

끓는 점: 713.9±60.0 °C(Predicted)

밀도: 1.637±0.06 g/cm3(Predicted)

용해도: DMSO : 50 mg/mL (150.93 mM; Need ultrasonic)

산도 계수 (pKa): 3.92±0.10(Predicted)

InChI: InChI=1S/C15H13N3O6/c19-10-5-4-9(13(22)17-10)18-14(23)7-2-1-3-8(12(7)15(18)24)16-6-11(20)21/h1-3,9,16H,4-6H2,(H,20,21)(H,17,19,22)

InChIKey: LRGLFYOYKPSPJQ-UHFFFAOYSA-N

SMILES: C(O)(=O)CNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

안전

Thalidomide-NH-CH2-COOH C화학적 특성, 용도, 생산

정의

Thalidomide-NH-CH2-COOH contains a thalidomide group, an amide, an alkylC2 chain, and a terminal carboxylic acid. This product is ready for conjugation to target proteins for PROTAC R&D. It is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. This compound also can be connected to the ligand for protein by a linker to form PROTACs, such as THAL-SNS-032 (HY-123937).

Thalidomide-NH-CH2-COOH 준비 용품 및 원자재

원자재

준비 용품

Thalidomide-NH-CH2-COOH 공급 업체

글로벌( 25)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +86-13783527580	Lingzhiyue@aliyun.com	China	3147	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Suzhou Origin Specialty Chemicals Co., Ltd.	+86-512-68662322 +86-17312436797	hanqun@origsc.com	China	788	58
Suzhou ARTK Medchem Co., Ltd.	+8618168183658	sales1@artkmedchem.com	China	39009	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9838	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1362	58
Lingyuan Bebiansen Biological Technology Co., Ltd	18642120371	2837458851@qq.com	China	9802	58
Shanghai Haohong Pharmaceutical Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	39997	58
Hefei Mokai Pharmaceutical Technology Co., Ltd	18130062233	3362556465@qq.com	China	8000	58