ANTI-PRL-3;Anti-PRL-R;ANTI-PTP4A3;Anti-hPRLrI;Anti-PRLR antibody produced in rabbit;ANTI-PHOSPHATASE OF REGENERATING LIVER;Anti-PTP4A3 antibody produced in rabbit;Anti-PTP4A3 antibody produced in chicken;Anti-PRL-3 antibody produced in rabbit;Anti-PRL3/PTP4A3 antibody produced in goat
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
ANTI-PHOSPHATASE OF REGENERATING LIVER C화학적 특성, 용도, 생산
용도
Anti-PRL-3 antibody produced in rabbit has been used in western blotting and immunohistochemistry.
일반 설명
Phosphatase of regenerating liver (PRL-3), also known as protein tyrosine phosphatase type IVA, member 3 (PTP4A3) is a dual-specificity phosphatase. It belongs to the phosphatases of regenerating liver family. The PTP4A3 gene is localized on human chromosome 8q24.3.
Biochem/physiol Actions
Phosphatase of regenerating liver (PRL-3) promotes epithelial-mesenchymal transition. It also plays an essential role in cancer cell migration, invasion and metastasis. It dephosphorylates serine, threonine and tyrosine residues. The protein is overexpressed in various cancers. PTP4A3 associates with transcription factors and regulates gene transcription. In addition, it also regulates breast cancer cell proliferation and invasion. Thus, this protein acts as a potent therapeutic target for breast cancer.
ANTI-PHOSPHATASE OF REGENERATING LIVER 준비 용품 및 원자재
