NeuraMinidase (Sialidase) C화학적 특성, 용도, 생산
용도
Neuraminidase (Sialidase) has been used to desialylate transferrin in order to study its isoforms in human serum.
일반 설명
Neuraminidase is an acylneuraminyl hydrolase which hydrolyzes terminal
N- or
O-acylneuraminic acids which are α2,3-, α2,6-, or α2,8-linked (rate: α2,6 > α2,3 > α2,8) to oligosaccharides, polysaccharides, mucopolysaccharides, glycoproteins, and glycolipids. Noteworthy, for the hydrolysis of glycolipids, the presence of a detergent is necessary. Because of the broad substrate specificity, the enzyme is very well suited for the complete removal of sialic acids from glycoconjugates of a wide variety of biological materials (
e.g., in cytology, on cell surfaces, viruses
etc.).
Biochem/physiol Actions
Neuraminidase breaks α-ketosidic linkage between N-acetylneuraminic acid and the adjacent sugar residue.
NeuraMinidase (Sialidase) 준비 용품 및 원자재
원자재
준비 용품
