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FMoc-Val-Cit-PAB-MMAE

FMoc-Val-Cit-PAB-MMAE 구조식 이미지

카스 번호:: 1350456-56-2

상품명:: FMoc-Val-Cit-PAB-MMAE

동의어(영문):: Fmoc-VC-PAB-MMAE;FMoc-Val-Cit-PAB-MMAE;Fmoc-Val-Cit-PABC-MMAE;Drug-Linker Conjugates for ADC,inhibit,FmocValCitPABMMAE,Inhibitor,Fmoc Val Cit PAB MMAE;L-Valinamide, N-[[[4-[[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-meth...;N-[[[4-[[N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide

CBNumber:: CB32730902

분자식:: C73H104N10O14

포뮬러 무게:: 1345.67

MOL 파일:: 1350456-56-2.mol

속성

안전

용도

공급 업체 64

FMoc-Val-Cit-PAB-MMAE 속성

끓는 점: 1353.5±65.0 °C(Predicted)

밀도: 1.198±0.06 g/cm3(Predicted)

산도 계수 (pKa): 10.63±0.46(Predicted)

안전

FMoc-Val-Cit-PAB-MMAE C화학적 특성, 용도, 생산

개요

Fmoc-Val-Cit-PAB-MMAE is a type of small molecule drug that can selectively target cancer cells while minimizing damage to healthy cells. The Fmoc group is a commonly used protective group in peptide synthesis and is often used to protect N-terminal amino groups. Val and Cit groups are common amino acids in peptides and proteins. The Fmoc group protects the amino group and helps to ensure that the drug is delivered intact to its target, while the Val and Cit amino acids provide a binding site for the drug to target specific cancer cells. The PAB linker (a para-aminobenzoic acid group) ensures that the MMAE cytotoxic drug is delivered specifically to cancer cells, where it can exert its toxic effects and inhibit the growth of cancer cells.

용도

Fmoc-Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate containing a cleavable Val-Cit peptide, a PABC linker and a MMAE payload. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells.

FMoc-Val-Cit-PAB-MMAE 준비 용품 및 원자재

원자재

준비 용품

FMoc-Val-Cit-PAB-MMAE 공급 업체

글로벌( 64)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Xilinglab Co., Ltd.	+8618381337976	bd@xilinglab.com	China	86	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Changzhou AniKare Pharmatech Co., Ltd.	+86-0519-8359-8696 +8618018249389	sales@anikare.com	China	8393	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068 +86-15680926068	1924344760@confluore.cn	China	2996	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58