PFE-360
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PFE-360 속성
- 저장 조건
- room temp
- 용해도
- DMSO: 2mg/mL, 투명
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
안전
PFE-360 C화학적 특성, 용도, 생산
개요
PFE-360 (PF-06685360) is a poten and elective inhibitor of LRRK2 kinase.in vitro
PFE-360 (4 mg/kg and 7.5 mg/kg, orally, BID, 10-12 weeks) treatment potently decreases the LRRK2-pSer935/total LRRK2 ratio, with no significant adverse effects.animal Model: Female Sprague Dawley rats (NTac:SD) weighed 225-250 g.
Dosage: 4 mg/kg and 7.5 mg/kg (pharmacokinetics and pharmacodynamics).
Administration: Orally BID for 10-12 weeks.
Result: The LRRK2-pSer935/total LRRK2 ratio was significantly decreased at both 1 h and 12 h after dosing.
The terminal bodyweights exhibited no significant changes.
PFE-360 준비 용품 및 원자재
원자재
준비 용품
PFE-360 공급 업체
글로벌( 18)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 |
CHINA | 2029 | 58 | |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 |
3003855609@qq.com | China | 7892 | 56 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 |
China | 4121 | 55 | |
| Shanghai Beckham Medical Technology Co., Ltd | 021-13816613772 13816613772 |
huahero21@sina.com | China | 357 | 55 |
| UHN Shanghai Research & Development Co., Ltd. | 021-58958002 18930822973 |
xiaoyangw@gmail.com | China | 2129 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 |
liming@bio-fount.com | China | 9730 | 58 |
| Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd. | 15990591583 |
China | 5562 | 58 | |
| Hefei fuya biotechnology co. LTD | 18096409024 |
sales02@foreversyn.com | China | 1938 | 58 |