MAGAININ II

MAGAININ II 구조식 이미지
카스 번호:
108433-95-0
상품명:
MAGAININ II
동의어(영문):
MAGAININ 2;Aids007842;MAGAININ II;Aids-007842;Magainin II peptide;MAGAININ II USP/EP/BP;GIGKFLHSAKKFGKAFVGEIMNS;Magainin II, ≥97% (HPLC);Magainin 2 (Xenopus laevis);Magainin 2 peptide, Xenopus
CBNumber:
CB3664319
분자식:
C114H180N30O29S
포뮬러 무게:
2466.9
MOL 파일:
108433-95-0.mol
MSDS 파일:
SDS

MAGAININ II 속성

끓는 점
2444.0±65.0 °C(Predicted)
밀도
1.275±0.06 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMSO에 용해됨
시퀀스
H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH

안전

WGK 독일 3

MAGAININ II C화학적 특성, 용도, 생산

일반 설명

Magainin II is a member of the antimicrobial peptides family. It is a cationic peptide with Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser amino acid sequence. Magainin II is water soluble and non-hemolytic at its effective and amphiphilic antimicrobial concentrations.

Biochem/physiol Actions

Magainin II acts as an antibiotic in a variety of organisms. Magainin II exhibits cytotoxic and anti-proliferative effects via pore formation in bladder cancer cells. In mice, it acts as an anti-tumor agent in several cancer cell lines and tumors. Magainin II facilitates lactate dehydrogenase discharge from mammalian cells. It directly interacts with certain cell membranes via amphiphilic α-helix and forms permeable ion channels, which results in depolarization and irreversible cytolysis and finally cell death. At low concentrations, Magainin II retards the growth of bacterial and fungal species and it promotes cytolysis in protozoa.

MAGAININ II 준비 용품 및 원자재

원자재

준비 용품


MAGAININ II 공급 업체

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Hangzhou Go Top Peptide Biotech
0571-88211921
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+8618108235634
Cecilia@youngshechem.com China 2345 58
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support@tgpeptide.com China 3279 58

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