N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine 구조식 이미지
카스 번호:
519178-28-0
상품명:
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
동의어(영문):
TNP;IP6K Inhibitor;IP3K Inhibitor;TNP >=95% (HPLC);IP6K1 inhibitor TNP;IP6K1 inhibitor TNP (TNP);IP6K Inhibitor - CAS 519178-28-0 - Calbiochem;N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine;N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
CBNumber:
CB41128943
분자식:
C20H16F3N7O2
포뮬러 무게:
443.38
MOL 파일:
519178-28-0.mol
MSDS 파일:
SDS

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine 속성

끓는 점
723.4±70.0 °C(Predicted)
밀도
1.543±0.06 g/cm3(Predicted)
저장 조건
2-8°C
용해도
DMSO: ≥10mg/mL
산도 계수 (pKa)
10.51±0.10(Predicted)
물리적 상태
노란색 고체
색상
노란색
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T
위험 카페고리 넘버 25-36
안전지침서 26-45
유엔번호(UN No.) UN 2811 6.1 / PGIII
WGK 독일 3
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H300 삼키면 치명적임 급성 독성 물질 - 경구 구분 1,2 위험 GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
예방조치문구:
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P301+P310 삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
4 0

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine C화학적 특성, 용도, 생산

용도

TNP provides a means of selectively and rapidly modulating cellular InsP7 levels in vivo without affecting levels of other inositol phosphates.

Biochem/physiol Actions

TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates.

N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine 준비 용품 및 원자재

원자재

준비 용품


N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine 공급 업체

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