REVEROMYCIN A

REVEROMYCIN A 구조식 이미지
카스 번호:
134615-37-5
상품명:
REVEROMYCIN A
동의어(영문):
REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
CBNumber:
CB4443481
분자식:
C36H52O11
포뮬러 무게:
660.79
MOL 파일:
134615-37-5.mol

REVEROMYCIN A 속성

끓는 점
849.0±65.0 °C(Predicted)
밀도
1.21±0.1 g/cm3(Predicted)
저장 조건
−20°C
용해도
에 용해됨DMF
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
4.36±0.17(Predicted)
색상
갈색을 띤 노란색

안전

WGK 독일 3

REVEROMYCIN A C화학적 특성, 용도, 생산

용도

Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.

REVEROMYCIN A 준비 용품 및 원자재

원자재

준비 용품


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