ANTI-CALNEXIN C화학적 특성, 용도, 생산
용도
Anti-Calnexin antibody produced in rabbit has been used in:
- western blot analysis
- immunofluorescence
- dual immunofluorescence staining
일반 설명
Calnexin contains a long (461 amino acids) N-terminal Ca
2+ -binding domain extending into the lumen of the endoplasmic reticulum (ER), a short (22 amino acids) transmembrane segment and an acidic cytosolic domain (96 amino acids).
Biochem/physiol Actions
Calnexin binds newly synthesized glycoproteins and misfolded proteins and is believed to play a critical role in quality control processes during protein synthesis and folding. Calnexin acts as a lectin-like chaperone that binds oligosaccharide residues of newly synthesized N-linked glycoproteins. Calnexin has been shown to be associated with several cell surface proteins, including major histocompatibility complex (MHC) class I heavy chain, T-cell receptor (TCR), and B cell membrane immunoglobulin during translocation through the endoplasmic reticulum (ER). It also forms complexes with other resident ER proteins involved in Ca2+ -dependent retention of proteins.
ANTI-CALNEXIN 준비 용품 및 원자재
원자재
준비 용품
