Denatonium Benzoate Monohydrate
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Denatonium Benzoate Monohydrate 속성
- 용해도
- 클로로포름 및 메탄올에 매우 용해됩니다. 에탄올(95%) 및 물에 용해됩니다. 아세톤에 난용성; 에테르에는 거의 녹지 않습니다.
안전
Denatonium Benzoate Monohydrate C화학적 특성, 용도, 생산
화학적 성질
Denatonium benzoate occurs as an odorless, very bitter tasting, white crystalline powder or granules.용도
Pharmaceutic aid (alcohol denaturant); pharmaceutic aid (flavor).생산 방법
Denatonium benzoate was first synthesized in the 1950s and is usually prepared by reacting denatonium chloride with benzyl benzoate.Pharmaceutical Applications
Denatonium benzoate is among the most bitter of substances known and is detectable at concentrations of approximately 10 ppb. In pharmaceutical and other industrial applications it is added to some products as a deterrent to accidental ingestion. It is most commonly used at levels of 5–500 ppm. Denatonium benzoate may also be used to replace brucine or quassin as a denaturant for ethanol.In pharmaceutical formulations, denatonium benzoate has been used as a flavoring agent in placebo tablets, and in a topical formulation it has been used in an anti-nailbiting preparation.
Safety
Denatonium benzoate is generally regarded as a nonirritant and nonmutagenic substance.However,there has been a single report of contact urticaria attributed to denatonium benzoate occurring in a 30-year-old man who developed asthma and pruritus after using an insecticidal spray denatured with denatonium benzoate.LD50 (rabbit, oral): 0.508g/kg
LD50 (rat, oral): 0.584g/kg
저장
Denatonium benzoate is stable up to 140°C and over a wide pH range. It should be stored in a well-closed container (such as polythene-lined steel) in a cool, dry place. Aqueous or alcoholic solutions retaintheir bitterness forseveral years evenwhenexposed to light.비 호환성
Denatonium benzoateis incompatible with strongoxidizing agents.Regulatory Status
Denatonium benzoate is used worldwide as a denaturant for alcohol. It is included in the FDA Inactive Ingredients Database (topical gel and solution).Denatonium Benzoate Monohydrate 준비 용품 및 원자재
원자재
준비 용품
Denatonium Benzoate Monohydrate 공급 업체
글로벌( 6)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 |
sj_scrc@sinopharm.com | China | 9823 | 79 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 |
sales@rrkchem.com | China | 55827 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing@energy-chemical.com | China | 44941 | 58 |