피부(또는 머리카락)에 묻으면 오염된 모든 의복은 벗거나 제거하시오 피부를 물로 씻으시오/샤워하시오.
P305+P351+P338
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
2
3
0
Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine C화학적 특성, 용도, 생산
개요
Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine is a useful research chemical for organic synthesis and other chemical processes.
용도
trans-N,N′-dimethylcyclohexane-1,2-diamine can be used as a ligand in the synthesis of the following products via copper catalyzed C-N coupling reactions:
vinylsulfoximines obtained from NH sulfoximes and vinyl bromides
N-arylpyridones obtained via reaction between 2-substituted pyridines and aryl halides
N-aryl amines obtained via reaction between amines and aryl iodides/aryl bromides
Synthesis
Cyclohexene oxide (1) was reacted with 25–30% aqueous methylamine (1.5 equiv.) in a sealed reactor to form trans-2-(methylamino)cyclohexanol 2 at 80 °C within 5h. Compound 2 was subjected to Mitsunobu reaction at room temperature, followed by adjusting the pH from 2 to 10 to yield 7-methyl-7-azabicyclo[4.1.0]-heptane 3, which was directly subjected to the following reaction without purification. Ring-opening reactions of compound 3 with a methylamine aqueous solution were completed in a sealed reactor at 110 °C after 6h to yield Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine.
Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine 준비 용품 및 원자재
원자재
준비 용품
Trans-(1R,2R)N,N'-Dimethyl-cyclohexane-1,2-diamine 공급 업체
