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NF 279

NF 279 구조식 이미지

카스 번호:: 202983-32-2

상품명:: NF 279

동의어(영문):: NF 279;CS-319;NF279 - CAS 202983-32-2 - Calbiochem;8,8[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhex;8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid;8,8'-(CARBONYLBIS(IMINO-4,1-PHENYLENECARBONYLIMINO-4,1-PHENYLENECARBONYLIMINO))BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, NA;8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid sodium salt;8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt;8,8'-[CARBONYLBIS(IMINO-4,1-PHENYLENECARBONYLIMINO-4,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID HEXASODIUM SALT;8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalene-trisulphonic acid hexasodium salt

CBNumber:: CB6135641

분자식:: C49H37N6NaO23S6

포뮬러 무게:: 1293.2

MOL 파일:: 202983-32-2.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 48

NF 279 속성

저장 조건: Desiccate at -20°C

용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(약간 용해됨)

물리적 상태: 흰색 고체

수용성: Soluble to 25 mM in water

안정성: 흡습성

안전

NF 279 C화학적 특성, 용도, 생산

용도

NF 279 is a potent and selective P2X1 antagonist.

일반 설명

A suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC₅₀/K_B ~1 μM in smooth muscle). Effectively discriminates between P2Y and P2X receptors with no discernible effects on α_1A adrenoceptors, adenosine A₁ and A_2B receptors, histamine H₁, muscarinic M₃ and neuronal nicotinic acetylcholine receptors. Displays a selectivity profile of P2X₁ >P2X₂ >P2X₃ >P2X₄ (IC₅₀ = 19 nM, 770 nM, 1.62 μM and >300 μM, respectively) in Xenopus oocytes pre-incubated with ATP. In rat and human tissues, exhibits a potency profile of rat P2X₁ > human P2X₁ ? rat P2X₂ > rat P2X₃ ~human P2X₇ ? human P2X₄. Not degraded by ecto-nucleotidases.

생물학적 활성

A potent and selective P2X 1 antagonist (IC 50 = 19 nM). Displays good selectivity over P2X 2 ,(IC 50 = 0.76 μ M), P2X 3 (IC 50 = 1.62 μ M), P2X 4 (IC 50 > 300 μ M), P2Y receptors and ecto-nucleotidases.

NF 279 준비 용품 및 원자재

원자재

준비 용품

NF 279 공급 업체

글로벌( 48)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58
Jinan Mingya Medical Technology Co., Ltd.	0531-85828981	864598798@qq.com	China	588	58
AdooQ Bioscience CHINA	025-58849295 18951903616;	info@adooq.cn	China	2989	60
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
BOC Sciences	--	info@bocsci.com	USA	0	65
Changzhou Chenhong Biotechnology Co., Ltd.	0519-85788828 13775037613	sales@chemrenpharm.com	China	3538	58
Cckinase, Inc.	+1 (732)236-3202	sales@cckinase.com	United States	2738	58

NF 279 관련 검색:

1,5-나프탈렌다이설폰산 디나트륨 1,5-나프탈렌디설폰산 4-ACETAMIDOBENZENESULFINIC ACID SODIUM SALT sodium N-benzylsulphanilate p-Aminobenzoyl benzamide Naphthalene-1,3,5-trisulphonic acid NF 279 1,5-Naphthalenedisulfonic acid tetrahydrate 1,3-di-p-tolylurea 1,5-NAPHTHALENEDISULFONIC ACID DISODIUM SALT, DIHYDRATE, 98 1-Naphthylamine-4,6,8-trisulfonic acid 8-AMINO-1,5-NAPHTHALENEDISULFONIC ACID MONOSODIUM SALT