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스핑가닌

스핑가닌 구조식 이미지

카스 번호:: 3102-56-5

한글명:: 스핑가닌

동의어(한글):: 스핑가닌

상품명:: DL-ERYTHRO-DIHYDROSPHINGOSINE

동의어(영문):: DIHYDROSPHINGOSINE;D-ERYTHRO-SPHINGANINE;D-ERYTHRO-DIHYDROSPHINGOSINE;DL-ERYTHRO-1,3-DIHYDROXY-2-AMINOOCTADECANE;DL-SPHINGANINE;D,L-ERYTHRO-SPHINGANINE;DL-ERYTHRO-DIHYDROSPHINGOSINE;DIHYDROSPHINGOSINE, D-ERYTHRO;D-ERYTHRO-SPHINGOSINE, DIHYDRO-;D-ERTYTHRO-SPHINGANINE, C18 CHAIN

CBNumber:: CB6139144

분자식:: C18H39NO2

포뮬러 무게:: 301.51

MOL 파일:: 3102-56-5.mol

속성

안전

용도

공급 업체 71

스핑가닌 속성

녹는점: 70-72°C

끓는 점: 446.2±25.0 °C(Predicted)

밀도: 0.927±0.06 g/cm3(Predicted)

저장 조건: −20°C

용해도: 클로로포름/메탄올(9:1): 20mg/mL, 투명, 무색 ~ 희미한 노란색

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 12.57±0.45(Predicted)

색상: 하얀색

수용성: 물에 용해됨(일부 혼화성), 클로로포름, 100% 따뜻한 에탄올(25mg/ml), 따뜻한 DMSO(25mg/ml) 및 메탄올.

InChI: InChI=1/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18+/s3

InChIKey: OTKJDMGTUTTYMP-LHIQYTEENA-N

SMILES: C(O)[C@@H](N)[C@@H](O)CCCCCCCCCCCCCCC |&1:2,4,r|

CAS 데이터베이스: 3102-56-5(CAS DataBase Reference)

안전

WGK 독일	3

스핑가닌 C화학적 특성, 용도, 생산

개요

DL-erythro Sphinganine (d18:0) is a precursor of ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate . Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well as in some cancers. This product is a mixture of sphinganine (d18:0) , L-erythro sphinganine (d18:0) , D-threo sphinganine (d18:0) , and L-threo sphinganine (d18:0). [Matreya, LLC. Catalog No. 1324]

화학적 성질

White Powder

용도

DL-erythro-Dihydrosphingosine is an inhibitor of PKC (protein kinase C). This compound also blocks PLA2 (phospholipases A2) and the D-sphingosine precursor.

생물학적 활성

Protein kinase C inhibitor.

Purification Methods

Purify it by recrystallisation from pet ether/EtOAc or CHCl3. The (±)-N-dichloroacetyl derivative has m 142-144o (from MeOH). [Shapiro et al. J Am Chem Soc 80 2170 1958, Shapiro & Sheradsky J Org Chem 28 2157 1963.] The D-isomer crystallises from pet ether/Et2O and has m 78.5-79o, [] 28 +6o (CHCl3/MeOH, 10:1). [Grob & Jenny Helv Chim Acta 35 2106 1953, Jenny & Grob Helv Chim Acta 36 1454 1953, Beilstein 4 I 448, 4 II 757, 4 III 854, 4 IV 1887.]

스핑가닌 준비 용품 및 원자재

원자재

준비 용품

스핑가닌 공급 업체

글로벌( 71)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29016	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Changzhou AniKare Pharmatech Co., Ltd.	+86-0519-8359-8696 +8618018249389	sales@anikare.com	China	8390	58
Chongqing Zhihe Biopharmaceutical Co., Ltd.	+86-18580541567 +86-17782035140	sales@zhswyy.com	China	338	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32360	55
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69

스핑가닌 관련 검색:

N-(6-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]CAPROYL)-PHYTOSPHINGOSINE Phytosphingosine C2 DIHYDROCERAMIDE C14 Dihydroceramide DL-ERYTHRO-DIHYDROSPHINGOSINE C12 NBD-L-THREO-DIHYDROSPHINGOSINE C6 NBD-D-ERYTHRO-DIHYDROSPHINGOSINE C6 NBD-L-THREO-DIHYDROSPHINGOSINE C12 NBD-D-ERYTHRO-DIHYDROSPHINGOSINE D-ERYTHRO-SPHINGOSINE D-erythro-Dihydro-D-sphingosine-1-phosphate C6 DIHYDROCERAMIDE KRN7000 C8 DIHYDROCERAMIDE C6 NBD SAFINGOL C18 Dihydroceramide C4 Dihydroceramide N-[12-[(7-NITRO-2-1,3-BENZOXADIAZOL-4-YL)AMINO]DODECANOYL]-SPHINGANINE