N-(1-페닐에틸)-2-(피롤리딘-1-일)퀴나졸린-4-아민
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N-(1-페닐에틸)-2-(피롤리딘-1-일)퀴나졸린-4-아민 속성
- 끓는 점
- 516.8±42.0 °C(Predicted)
- 밀도
- 1?+-.0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- 에 용해됨 DMSO: >5mg/mL
- 산도 계수 (pKa)
- 7.27±0.59(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 -20°에서 최대 3개월 동안 보관할 수 있습니다.
안전
WGK 독일 | 3 |
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N-(1-페닐에틸)-2-(피롤리딘-1-일)퀴나졸린-4-아민 C화학적 특성, 용도, 생산
개요
Importazole is a cell-permeable inhibitor of importin-β, which transports cargo molecules bearing a nuclear localization signal into the nucleus. Importazole prevents nuclear import of GFP-tagged nuclear factor of activated T cells (NFAT-GFP) in HEK293 cells (IC50 = 15 μM), which is reversible upon importazole washout. Importazole does not interfere with transportin-mediated nuclear import or chromosomal maintenance 1 (CRM1)-mediated nuclear export. Importazole inhibits nuclear import of topoisomerase IIβ binding protein 1 (TopBP1) in Xenopus egg extracts and of NF-κB in multiple myeloma cells. It also induces defects in spindle and microtubule formation in vitro.용도
Importazole is an importin-β inhibitor.Biochem/physiol Actions
Importazole is an inhibitor of importin-β transport receptors. During interphase, the transport receptor importin-β carries cargoes into the nucleus, where RanGTP releases them. Importazole somehow disrupts the importin/RAN interaction. Importazole is selective among other transporters. Compounds are imported into, but not out of, cells.N-(1-페닐에틸)-2-(피롤리딘-1-일)퀴나졸린-4-아민 준비 용품 및 원자재
원자재
준비 용품
N-(1-페닐에틸)-2-(피롤리딘-1-일)퀴나졸린-4-아민 공급 업체
글로벌( 73)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29823 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 |
18522618860@163.com | China | 694 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |