(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone 구조식 이미지
카스 번호:
71801-45-1
상품명:
(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone
동의어(영문):
Ixocarpalactone A;(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone;Ergost-2-en-26-oic acid, 5,6-epoxy-4,16,20,22,23-pentahydroxy-1-oxo-, γ-lactone, (4β,5β,6β,16β,22R,23R,25R)-
CBNumber:
CB72287404
분자식:
C28H40O8
포뮬러 무게:
504.62
MOL 파일:
71801-45-1.mol

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone 속성

녹는점
290-292 °C
끓는 점
741.4±60.0 °C(Predicted)
밀도
1.36±0.1 g/cm3(Predicted)
산도 계수 (pKa)
13.47±0.70(Predicted)

안전

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone C화학적 특성, 용도, 생산

Anticancer Research

This terpenoid compound is isolated from the edible plant Physalis philadelphica.The leaf and stem extract induces quinine reductase, a phase II enzyme, needed formetabolism of chemical carcinogens. The anticancer activity of ixocarpalactone isexerted through G2/M phase arrest in cell cycle, downregulation of E2F-1, DP-1,upregulation of hyper-phosphorylated retinoblastoma, and induction of apoptosis inSW480 human colon cancer cells (Balunas and Kinghorn 2005; Choi et al. 2006).

(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone 준비 용품 및 원자재

원자재

준비 용품


(22R,23R,25R)-5β,6β-Epoxy-4β,16β,20,22,23-pentahydroxy-1-oxoergost-2-en-26-oic acid γ-lactone 공급 업체

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