7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride
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7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride 속성
- 끓는 점
- 530.9±50.0 °C(Predicted)
- 밀도
- 1.207
- 저장 조건
- Store at -20°C
- 용해도
- DMSO: 용해성15mg/mL, 투명
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 14.68±0.40(Predicted)
- 색상
- 흰색에서 베이지색
안전
| WGK 독일 | 3 |
|---|
7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride C화학적 특성, 용도, 생산
용도
A selective nociceptin/orphanin FQ receptor antagonist, 7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride can act as a potentially useful adjunct to chronic pain therapy with opioids and can be used to treat conditions in which thermal hyperalgesia is a significant component of the pain response.Biochem/physiol Actions
SB-612111 is a potent antagonist of the nociceptin receptor ORL-1. SB-612111 binds to ORL-1 with high affinity (Ki = 0.33 nM) but has very low affinity for classic opioid receptors. The compound SB-612111 antagonizes the anti-morphine effects of nociceptin and blocks nociceptin-induced thermal hyperalgesia.7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride 준비 용품 및 원자재
원자재
준비 용품
7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride 공급 업체
글로벌( 27)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 |
shchemsky@sina.com | China | 15421 | 60 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 |
China | 9901 | 58 | |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| EMMX Biotechnology LLC | 888-539-0666 |
info@emmx.com | United States | 8449 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9709 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 |
info@amateksci.com | China | 28821 | 58 |
| Aishilun biotechnology (Shanghai) co., LTD | 021-50676523 18019098996 |
info@acelybio.com | China | 3967 | 58 |
| DC Chemicals | 021-58447131 13564518121 |
sales@dcchemicals.com | China | 9414 | 58 |
| Wuhan Topule | +86-02787215551 +86-19945035818 |
2936752263@qq.com | China | 7954 | 58 |