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4'-Bromo-3'-methylacetophenone

4'-Bromo-3'-methylacetophenone 구조식 이미지

카스 번호:: 37074-40-1

상품명:: 4'-Bromo-3'-methylacetophenone

동의어(영문):: NSC 405623;Fluralaner-003;Fluralaner Impurity 29;3-Methyl-4-bromoacetophenone;4'-Bromo-3'-methylacetophenone;4'-BROMO-3'-METHYLACETOPHENONE;Ethanone, 1-(4-broMo-3-Methylphenyl)-

CBNumber:: CB7947102

분자식:: C9H9BrO

포뮬러 무게:: 213.07

MOL 파일:: 37074-40-1.mol

속성

안전

용도

공급 업체 98

4'-Bromo-3'-methylacetophenone 속성

녹는점: 31-32 °C

끓는 점: 157-159 °C(Press: 19 Torr)

밀도: 1.388±0.06 g/cm3(Predicted)

저장 조건: Sealed in dry,Room Temperature

용해도: 클로로포름(약간 용해됨), 메탄올(약간 용해됨)

물리적 상태: 융합된 고체

색상: Pale lemon

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

HS 번호	2914390090

그림문자(GHS):

신호 어:

Warning

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H302	삼키면 유해함	급성 독성 물질 - 경구	구분 4	경고	P264, P270, P301+P312, P330, P501
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P260	분진·흄·가스·미스트·증기·...·스프레이를 흡입하지 마시오.
P271	옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.

4'-Bromo-3'-methylacetophenone C화학적 특성, 용도, 생산

용도

4'-Bromo-3'-methylacetophenone is a versatile building block that is used in the synthesis of many complex compounds. It can be used as a reactant, reagent, or speciality chemical.

Synthesis

A solution of 4-bromo-3-methylbenzaldehyde (4 g, 20 mmol) in dry tetrahydrofuran (40 mL) was cooled to 0??C under nitrogen atmosphere, and then methyl magnesium bromide (20 mL, 1N in tetrahydrofuran) was added dropwise. The ice bath was removed, and the mixture was stirred for 2 hours. Ammonium chloride aqueous (40 mL) was added and the mixture was extracted with dichloromethane (20 mL * 3). The organic phase was dried by sodium sulphate, filtered and concentrated to give a residue. The residue was purified by column chromatography (silica gel, petroleum ether/ethyl acetate = 5:1) to give 1-(4-bromo-3-methylphenyl)ethanol. Colorless oil, yield 4.0 g, 93%. Pyridinium chlorochromate (48 g, 223 mmol) was added to a solution of 1-(4-bromo-3-methylphenyl)ethanol (31.9 g, 148 mmol) in dichloromethane (800 mL). The mixture was stirred at room temperature for 2 hours. The mixture was concentrated to give a residue. The residue was purified by column chromatography (silica gel, petroleum ether/ethyl acetate = 25:1) to give 4'-Bromo-3'-methylacetophenone. Yield 27.3 g, 87%.
Synthesis_37074-40-1

Figure Synthesis of 4'-Bromo-3'-methylacetophenone

4'-Bromo-3'-methylacetophenone 준비 용품 및 원자재

원자재

Benzenemethanol, 4-bromo-α,3-dimethyl- N-(4-acetyl-2-methylphenyl)acetamide 4-Bromo-n-methoxy-n,3-dimethylbenzamide Ethanone, 1-(4-amino-3-methylphenyl)- (9CI) 4-BROMO-3-METHYL-BENZALDEHYDE 4-BROMO-3-METHYLBENZONITRILE 4-Bromo-3-methylbenzoic acid 메틸리튬 아세틸 염화물 메틸마그네슘브로마이드 2-METHYLACETANILIDE 메틸마그네슘요오다이드

준비 용품

4-acetyl-2-methylbenzoic acid

4'-Bromo-3'-methylacetophenone 공급 업체

글로벌( 98)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	2991	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15932	58
Fluoropharm Co., Ltd.	+86-0571-85586753; +8613336034509	sales@fluoropharm.com	China	1377	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1320	58
Allfluoro pharmaceutical co. ltd.	021-26137118 +8615821363818	sales@allfluoro.com	China	5791	58

4'-Bromo-3'-methylacetophenone 관련 검색:

1-(4-Chloro-2-trifluoromethyl-phenyl)-ethanone 4'-BroMo-2',5'-difluoroacetophenone 1-(3-Fluoro-5-hydroxyphenyl)ethanone 4-Acetyl-2-methylbenzonitrile Ethanone, 1-[3-hydroxy-4-(phenylMethoxy)phenyl]- 4'-CHLORO-2',5'-DIFLUOROACETOPHENONE 1-(4-Bromo-2-chlorophenyl)propan-1-one 1-(3-Hydroxy-5-Methylphenyl)ethanone 1-(3-broMo-5-nitrophenyl)ethan-1-one 5-BroMo-2-hydroxy-4-Methylacetophenone 1-(4-BROMO-3-METHYLPHENYL)-5-CHLORO-1-OXOPENTANE 4'-Bromo-3'-methylacetophenone 6-BROMO-5-METHYLISATIN 1-(4-BROMO-3-METHYLPHENYL)-7-CHLORO-1-OXOHEPTANE 4-BROMO-5-METHYLISATINIC ACID SODIUM SALT 1-(4-BROMO-3-METHYLPHENYL)-6-CHLORO-1-OXOHEXANE 6-BROMO-5-ETHYLISATIN 2-BROMO-3-METHYLANTHRAQUINONE