Ethyl 3-(pyridin-2-ylamino)propanoate
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Ethyl 3-(pyridin-2-ylamino)propanoate 속성
- 녹는점
- 48-50°C
- 끓는 점
- 125°C/0.2mmHg(lit.)
- 밀도
- 1.131±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Inert atmosphere,2-8°C
- 용해도
- DMSO및메탄올에 용해됨
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 6.26±0.10(Predicted)
- 색상
- 하얀색
- InChI
- InChI=1S/C10H14N2O2/c1-2-14-10(13)6-8-12-9-5-3-4-7-11-9/h3-5,7H,2,6,8H2,1H3,(H,11,12)
- InChIKey
- UITNIDFEANEWPC-UHFFFAOYSA-N
- SMILES
- C(OCC)(=O)CCNC1C=CC=CN=1
- LogP
- 1.54 at 22℃ and pH6
안전
HS 번호 | 2933.39.9200 |
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Ethyl 3-(pyridin-2-ylamino)propanoate C화학적 특성, 용도, 생산
화학적 성질
White Solid용도
Ethyl 3-(2-Pyridylamino)propanoate is an intermediate used in the synthesis of Dabigatran etexilate, as thrombin inhibitors. Ethyl Ester form of P993315.Synthesis
A method for preparing Ethyl 3-(pyridin-2-ylamino)propanoate comprises the following steps: using 2-aminopyridine and ethyl acrylate as raw materials, using anhydrous ethanol as a solvent, using trifluoromethanesulfonic acid as a catalyst, and heating in an oil bath to control the temperature at 120 to 160° C. for a catalytic reaction for 16 to 20 hours under nitrogen protection. The obtained reaction solution is washed with petroleum ether at a temperature of 35 to 40° C. and a pressure of 0.09 to 0.1 MPa, then concentrated under reduced pressure, and then washed with petroleum ether/ethyl acetate and recrystallized to obtain white flaky crystals of Ethyl 3-(pyridin-2-ylamino)propanoate.Ethyl 3-(pyridin-2-ylamino)propanoate 준비 용품 및 원자재
원자재
준비 용품
Ethyl 3-(pyridin-2-ylamino)propanoate 공급 업체
글로벌( 426)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Terma Medicare India Pvt.,Ltd | +8613916485955 |
shivshanghai@yahoo.com | India | 150 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5895 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20291 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21666 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 |
stella@zetchem.com | China | 2136 | 58 |
Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 |
christine@shengqipharm.com | CHINA | 491 | 58 |
Rionlon ( Tianjin ) Pharmaceutical Co., Ltd. | 0086-13512289226 |
yangli@rionlon.com | CHINA | 28 | 58 |
Ethyl 3-(pyridin-2-ylamino)propanoate 관련 검색:
2,3/에폭시프로필 메타크릴레이트
4-Aminobenzamidine dihydrochloride
N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]arbonyl]-N-2-pyridinyl-beta-alanine ethyl ester 4-methylbenzenesulfonate
Dabigatran ethyl AcOH Salt
3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester
ETHYL N-[4-(METHYLAMINO)-3-NITROBENZOYL]-N-PYRIDIN-2-YL-SS-ALANINATE
3-[(3-AMINO-4-METHYLAMINO-BENZOYL)-PYRIDIN-2-YL-AMINO]-PROPIONIC ACID ETHYL ESTER