ANTI-HISTONE H3

ANTI-HISTONE H3 구조식 이미지
카스 번호:
상품명:
ANTI-HISTONE H3
동의어(영문):
ANTI-HISTONE 3;ANTI-HISTONE H3;Anti-Histone H3 Pan;ANTI-PHOSPHOSERINE 10;ANTI-HISTONE H3, HUMAN;ANTI-HISTONE H3, BOVINE;ANTI-HISTONE H3, HUMAN (RABBIT);ANTI-HISTONE H3 (1-20) RABBIT PAB;Imprint? Anti-H3Pan antibody produced in rabbit;Anti-Histone H3 antibody produced in rabbit
CBNumber:
CB8154644
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

ANTI-HISTONE H3 속성

저장 조건
−20°C
물리적 상태
완충 수용액

안전

WGK 독일 3

ANTI-HISTONE H3 C화학적 특성, 용도, 생산

용도

Anti-Histone H3 antibody produced in rabbit has been used in immunoblotting and immunofluorescence microscopy.

일반 설명

Histone proteins are known to stabilize and regulate the nuclear DNA. Core histones, H2A, H2B, H3 and H4 aid the packaging of eukaryotic nuclear DNA into repeating nucleosome units while the linker histone, H1, binds to DNA between the nucleosomes. A diverse and elaborate array of post-translational modifications, including acetylation, phosphorylation and methylation, ubiquitination and ADP ribosylation occur in histones, particularly on the N-terminal tail domains of histones, particularly of H3 and H4.These modifications dictate chromatin states and the gene expression.
Phosphorylation of H3, mainly on Ser10 and Ser28, is localized to a small fraction of highly acetylated H3 and occurs primarily in response to mitogenic and stress stimuli. Phosphorylation of Ser10 is considered a crucial event for the onset of mitosis. It is tightly correlated with chromosome condensation during both mitosis and meiosis. Histone methylation, like acetylation, is a complex, dynamic process involved in a number of processes, including transcriptional regulation, chromatin condensation, mitosis ad heterochromatin assembly. Conserved lysine residues in the N-terminal tail domains of histone H3, Lys4, Lys9, and Lys27 are the preferred sites of methylation. Histone lysine residues can be mono-, di-, and tri-methylated at different heterochromatic subdomains, adding further complexity to the regulation of chromatin structure.

ANTI-HISTONE H3 준비 용품 및 원자재

원자재

준비 용품


ANTI-HISTONE H3 공급 업체

글로벌( 26)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Sigma-Aldrich 021-61415566 800-8193336
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