ethyl 2-ethyl-2-methylbutanoate

ethyl 2-ethyl-2-methylbutanoate C화학적 특성, 용도, 생산

Synthesis

ethyl 2-ethyl-2-methylbutanoate is prepared by the reaction of Ethyl 2-ethylbutanoate and Iodomethane. The specific synthesis steps are as follows:
After dissolving ethyl 2-ethylbutyrate (50.0g, 346mmol) in 600mL tetrahydrofuran, N2 was bubbled into the resulting solution for 3 minutes, Then it was cooled to -78°C and then 190mL of 2M lithium diisopropylamide in tetrahydrofuran was added dropwise under N2 protection and -78°C, After the addition is complete, keep the reaction mixture at -78°C and continue to react for 30 minutes. Then iodomethane (58.9g, 415mmol) was slowly added to it, After the addition was completed, the reaction was slowly raised to room temperature overnight. Then slowly add saturated ammonium chloride solution to quench the reaction, and then separate the liquids. Collect the organic phase, extract the aqueous phase twice with dichloromethane, combine the organic phases, dry and spin dry to obtain the product. This is the desired ethyl 2-ethyl-2-methylbutanoate (52.2 g, yield 95%).

ethyl 2-ethyl-2-methylbutanoate 준비 용품 및 원자재

원자재

준비 용품

ethyl 2-ethyl-2-methylbutanoate 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20366	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10247	58
Jiangsu Nata Opto-electronic Material Co.,Ltd.	+86-0512-62520998 +86-15030927757	gaoym@natachem.com	China	229	58
Shaanxi LuyuanBiomedicine Co., LTD	+86-13991827389 +86-13991827389	sxlysw@sxlysw.com.cn	China	50	58
Aikon International Limited	025-66113011 13155353615	qzhang@aikonchem.com	China	15396	58
Qi Qi hang Biotechnology Co., Ltd.	13291169750 18151111370	1046215251@qq.com	China	7804	58
Shanghai Kaiwei Chemical Technology Co., Ltd.	021-58461859 15821823057	service@aiviche.com	China	49323	58
Nataorganic material (suzhou) Co., Ltd.	13555462360	luojx@natachem.com	China	233	58