MITF M1;ANTI-MITF;Anti-WS2A;Anti-MITF antibody produced in rabbit;ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR;Microphthalmia-associated transcription factor;Anti-Microphthalmia-associated transcription factor antibody produced in rabbit
ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR C화학적 특성, 용도, 생산
용도
Anti-MITF antibody has been used in immunohistochemistry and chromatin immunoprecipitation.
일반 설명
MITF (microphthalmia-associated transcription factor) is a basic helix-loop-helix, leucine-zipper transcription factor. It is located on human chromosome 3p13.
Biochem/physiol Actions
MITF is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
ANTI-MICROPHTHALMIA TRANSCRIPTION FACTOR 준비 용품 및 원자재
