Gap19
|
|
Gap19 속성
- 끓는 점
- 1511.4±65.0 °C(Predicted)
- 밀도
- 1.212±0.06 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- ≥58.07 mg/mL in H2O; insoluble in EtOH; ≥26.55 mg/mL in DMSO
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 3.30±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
- 수용성
- 물에 2mg/ml까지 용해됨
안전
Gap19 C화학적 특성, 용도, 생산
용도
Gap19 is a short peptide that inhibits hemichannels specifically for connexin-43 (Cx43), a cardiac connexin involved with gap junction formation. Gap junctions facilitate the exchange of ions and metabolites between cytoplasm and extracellular milieu. Reagents that inhibit hemichannels may have cardioprotective properties.Biochem/physiol Actions
Gap19, nonapeptide from the cytoplasmic loop of Connexin-43, is a selective blocker of connexin 43 (Cx43) hemichannel that does not block GJ or Cx40/Panx-1 channels in cardiomyocytes and astrocytes. Gap19 prevents Cx43 hemichannel opening and protect against myocardial ischemia/reperfusion injury.Gap19 준비 용품 및 원자재
원자재
준비 용품
Gap19 공급 업체
글로벌( 49)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10248 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
BOC Sciences | +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10523 | 58 |
Nanjing TGpeptide | +86-13347807150 +86-13347807150 |
support@tgpeptide.com | China | 3279 | 58 |
Sichuan Jisheng Biopharmaceutical | +86-0833-2598903 +8619981963231 |
jane@jsjpharm.cn | China | 175 | 58 |
Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 |
sales-cpd@caerulumpharma.com | China | 3420 | 58 |
Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 |
sales@reading-chemicals.com | China | 15185 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |