Chelerythrine
Chelerythrine
- CAS:
- 34316-15-9
- MF:
- C21H18NO4+
- MW:
- 348.37192
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Properties
- Melting point:
- 195-205°C
- Boiling point:
- 496.37°C (rough estimate)
- Density
- 1.2985 (rough estimate)
- refractive index
- 1.5614 (estimate)
- storage temp.
- Desiccate at -20°C
- solubility
- Chloroform (Slightly, Sonicated), DMSO (Slightly, Sonicated), Methanol (Slightly）
- form
- Solid
- color
- Light Yellow to Dark Orange
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C21H18NO4/c1-22-10-16-13(6-7-17(23-2)21(16)24-3)14-5-4-12-8-18-19(26-11-25-18)9-15(12)20(14)22/h4-10H,11H2,1-3H3/q+1
- InChIKey
- LLEJIEBFSOEYIV-UHFFFAOYSA-N
- SMILES
- C[N+]1=CC2=C(C(OC)=CC=C2C2C=CC3C=C4OCOC4=CC=3C1=2)OC
- LogP
- -0.401 (est)
- CAS DataBase Reference
- 34316-15-9(CAS DataBase Reference)
Safety Information
- Symbol(GHS)
GHS06,GHS07
- Signal word
- Danger
- Hazard statements
- H300-H315-H319-H335
- Precautionary statements
- P261-P264-P301+P310+P330-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22
- Safety Statements
- 36/37
Use
Chelerythrine chloride is the chloride form of Chelerythrine chloride which is a benzophenanthridine alkaloid isolated from the plant Chelidonium majus (greater celandine). It is a kind of potent, selective, and cell-permeable protein kinase C inhibitor, an efficient antagonist of G-protein-coupled CB1 receptors, and an independent activator of MAPK pathways. It has a wide range of biological activities including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. It has reported of that it is capable of inducing apoptosis in HL-60 human promyelocytic leukemia cells and several other cancer cell lines. The underlying mechanism is through its effects of inhibiting the binding of BclXL to Bax or Bad.
0 India supplier list of "Chelerythrine"
- Product Name:Chelerythrine Chloride
- Products Intro:Purity: 98% | Package: 1KG；100g;1g,100mg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Chelerythrine chloride
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Chelerythrine
- Products Intro:Purity: 98%（HPLC） | Package: 10mg;20mg;100mg;1g
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Chelerythrine chloride
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Chelerythrine
- Products Intro:Purity: 98% | Package: 10mg;20mg;50mg;100mg;200mg;500mg;1g;10g;100g;可按照客户要求定制包装
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Chelerythrine chloride
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Chelerythrine
- Products Intro:Purity: >=98% HPLC | Package: 10mg/50mg/100mg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:chelerythrine
- Products Intro:Purity: 98%
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Chelerythrine
- Company Type: Trader
- Country/Region: CHINA