R(+)-PROPRANOLOL HCL
R(+)-PROPRANOLOL HCL
- CAS:
- 5051-22-9
- MF:
- C16H21NO2
- MW:
- 259.34
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Properties
- Melting point:
- 96 °C
- Boiling point:
- 434.9±30.0 °C(Predicted)
- Density
- 1.093±0.06 g/cm3(Predicted)
- storage temp.
- Store at RT
- pka
- pKa 9.53±0.01(H2O,t=25±0.5,I=0.15(KCl))(Approximate)
Safety Information
Use
R(+)-PROPRANOLOL HCL(Inderal, others) is the prototypical andnonselective β-blocker. It blocks the β1- and β2-receptorswith equal affinity, lacks ISA, and does not block β-receptors. R(+)-PROPRANOLOL HCL like the other β-blockers discussed,is a competitive blocker whose receptor-blockingactions can be reversed with sufficient concentrations of β-agonists. Currently, R(+)-PROPRANOLOL HCL is approved for use inthe United States for hypertension, cardiac arrhythmias,angina pectoris, postmyocardial infarction, hypertrophiccardiomyopathy, pheochromocytoma, migraine prophylaxis,and essential tremor. In addition, because of its highlipophilicity (log P=3.10) and thus its ability to penetratethe CNS, propranolol has found use in treating anxiety andis under investigation for the treatment of a variety of otherconditions, including schizophrenia, alcohol withdrawalsyndrome, and aggressive behavior.
1 India supplier list of "R(+)-PROPRANOLOL HCL"
- Product Name:Propranolol
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Dexpropranolol
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Dexpropranolol
- Products Intro:Purity: >99%, 有含量赋值/不确定度, 检测方法: 元素分析法/质量平衡法(HPLC)/水含量/灰分分析/H-NMR/MS/ | Package: 100mg
- Company Type: Reagent
- Country/Region: CHINA