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6-Aminocaproic acid

CAS:
60-32-2
MF:
C6H13NO2
MW:
131.17

Properties

Melting point:
207-209 °C (dec.) (lit.)
Boiling point:
242.49°C (rough estimate)
Density 
1.042 g/cm3
vapor pressure 
<0.1 hPa (20 °C)
refractive index 
1.4870 (estimate)
Flash point:
207-209°C
storage temp. 
Store below +30°C.
solubility 
H2O: 50 mg/mL
form 
powder
pka
4.373(at 25℃)
color 
white
PH
7.0-7.5 (50g/l, H2O, 20℃)
Odor
Odorless
Water Solubility 
SOLUBLE
Merck 
14,432
BRN 
906872
InChIKey
SLXKOJJOQWFEFD-UHFFFAOYSA-N

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H320-H315-H319-H335
Precautionary statements 
P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P305+P351+P338+P337+P313
Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
2
RTECS 
MO6300000
TSCA 
Yes
HS Code 
29224995
Toxicity
LD50 in rats (g/kg): 7.0 i.p.; ~3.3 i.v. (Hallesy)

Use

6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.

351 supplier list of "6-Aminocaproic acid"

    US $40.00-308.00 / 1KG

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    US $0.00/ 25KG

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    US $625.00/ 1KG

  • Product Name:6-Aminocaproic acid
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  • Product Name:6-Aminocaproic acid
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