ANTIMYCIN A suppliers
ANTIMYCIN A
- CAS:
- 1397-94-0
- MF:
- C28H40N2O9
- MW:
- 548.6252
Company Type
Properties
- Melting point:
- 141-142℃
- Boiling point:
- 598.78°C (rough estimate)
- Density
- 1.6009 (rough estimate)
- refractive index
- 1.5800 (estimate)
- storage temp.
- 2-8°C
- solubility
- Ethanol: soluble
- form
- White to faint yellow powder.
- Water Solubility
- Soluble in 100% ethanol. Insoluble in water.
- Sensitive
- Light Sensitive
- Stability:
- Light Sensitive
Safety Information
- Symbol(GHS)
GHS06,GHS09
- Signal word
- Danger
- Hazard statements
- H300-H400
- Precautionary statements
- P264-P270-P273-P301+P310-P391-P405
- Hazard Codes
- T,N
- Risk Statements
- 25-50
- Safety Statements
- 26-36/37/39-45-61
- RIDADR
- UN 3462 6.1/PG 2
- WGK Germany
- 3
- RTECS
- CD0350000
- F
- 18
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 2941900000
- Toxicity
- LDLo orl-rat: 30 mg/kg 85ERAY 2,1078,78
Use
Antimycin A is a complex of related macrocyclic lactones, predominantly A1 to A4, isolated from several species of Streptomyces, first reported in the early 1950s for potent antifungal activity. There are over 20 known analogues in the antimycin A class, mostly involving variation of the fatty acid ester chain length or adjacent alkyl starting unit. Antimycin A binds to cytochrome C reductase at the Qi site, inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A is widely used as a bioprobe of respiration and other applications with over 5,000 literature citations.
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